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580560 TCEP, Hydrochloride - CAS 51805-45-9 - Calbiochem

A water-soluble and odorless disulfide-reducing agent that is more stable and effective than DTT.

TCEP, Hydrochloride - CAS 51805-45-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: tris(2-Carboxyethyl)phosphine, HCl

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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      51805-45-9C₉H₁₅O₆P · HCl
      Description
      OverviewA water-soluble and odorless disulfide-reducing agent that is more stable and effective than DTT. TCEP reduces even the most stable water-soluble alkyl disulfides at pH 4.5 within 5 minutes. TCEP is also capable of functioning as a reducing agent even in the pH range of 1.5-8.5. It is more resistant to air-oxidation as compared to DTT.
      Catalogue Number580560
      Brand Family Calbiochem®
      Synonymstris(2-Carboxyethyl)phosphine, HCl
      References
      ReferencesGetz, E.B., et al. 1999. Anal. Biochem. 273, 73.
      Han, J.C. and Han, G.Y. 1994. Anal. Biochem. 220, 5.
      Burns, J.A., et al. 1991. J. Org. Chem. 56, 2648.
      Product Information
      CAS number51805-45-9
      FormWhite crystalline solid
      Hill FormulaC₉H₁₅O₆P · HCl
      Chemical formulaC₉H₁₅O₆P · HCl
      Quality SegmentMQ100
      Applications
      Biological Information
      Purity≥98% by elemental analysis
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 34

      Causes burns.
      S PhraseS: 26-27-36/37/39

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Take off immediately all contaminated clothing.
      Wear suitable protective clothing, gloves and eye/face protection.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Corrosive
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). TCEP retains stability when stored at an acidic or alkaline pH; avoid storage at pH 7.0-8.0. Also avoid exposure to high concentrations of phosphate ions (>150 mM). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade ITEM Number
      Catalogue Number GTIN
      580560 0

      Documentation

      TCEP, Hydrochloride - CAS 51805-45-9 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      TCEP, Hydrochloride - CAS 51805-45-9 - Calbiochem Certificates of Analysis

      TitleLot Number
      580560

      References

      Reference overview
      Getz, E.B., et al. 1999. Anal. Biochem. 273, 73.
      Han, J.C. and Han, G.Y. 1994. Anal. Biochem. 220, 5.
      Burns, J.A., et al. 1991. J. Org. Chem. 56, 2648.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2008 RFH
      Synonymstris(2-Carboxyethyl)phosphine, HCl
      DescriptionA water-soluble and odorless disulfide reducing agent which is more stable and effective than DTT. TCEP reduces even the most stable water-soluble alkyl disulfides at pH 4.5 within 5 min. TCEP is also capable of functioning as a reducing agent even in pH range of 1.5-8.5. Is more resistant to air-oxidation as compared to DTT.
      FormWhite crystalline solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number51805-45-9
      Chemical formulaC₉H₁₅O₆P · HCl
      Purity≥98% by elemental analysis
      SolubilityH₂O (5 mg/ml)
      Storage Protect from moisture
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). TCEP retains stability when stored at an acidic or alkaline pH; avoid storage at pH 7.0-8.0. Also avoid exposure to high concentrations of phosphate ions (>150 mM). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Corrosive
      ReferencesGetz, E.B., et al. 1999. Anal. Biochem. 273, 73.
      Han, J.C. and Han, G.Y. 1994. Anal. Biochem. 220, 5.
      Burns, J.A., et al. 1991. J. Org. Chem. 56, 2648.