205531 Sigma-AldrichCA-074 Me - Calbiochem
CA-074 Me, CAS 147859-80-1, is a cell-permeable analog of CA-074 that acts as an irreversible inhibitor of intracellular cathepsin B.
More>> CA-074 Me, CAS 147859-80-1, is a cell-permeable analog of CA-074 that acts as an irreversible inhibitor of intracellular cathepsin B. Less<<CA-074 Me - Calbiochem: Ficha de dados de segurança do material (FDSM) ou ficha de segurança do material (FSM), certificado de análise (CA) e certificado de qualidade (CQ), dossiês e outros documentos disponíveis.
Sinônimos: Cathepsin B Inhibitor IV, [L-3-trans-(Propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline Methyl Ester
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Panorama geral
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Tabela com principais espec.
| Empirical Formula |
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| C₁₉H₃₁N₃O₆ |
Preço e Disponibilidade
| Número de catálogo | Disponibilidade | Embalagem | Qtde/Emb. | Preço | Quantidade | |
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| 205531-1MG |
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Ampola plástica | 1 mg |
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| Description | |
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| Overview | A cell-permeable analog of CA-074 (Cat. No. 205530) that acts as an irreversible inhibitor of intracellular cathepsin B. Reported to inhibit bone resorption in rodent models and shown to inhibit B16 melanoma cell invasion in vitro. |
| Catalogue Number | 205531 |
| Brand Family | Calbiochem® |
| Synonyms | Cathepsin B Inhibitor IV, [L-3-trans-(Propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline Methyl Ester |
| Product Information | |
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| ATP Competitive | N |
| Form | White solid |
| Hill Formula | C₁₉H₃₁N₃O₆ |
| Chemical formula | C₁₉H₃₁N₃O₆ |
| HS Code | 2933 99 99 |
| Reversible | N |
| Structure formula Image | |
| Quality Segment | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | cathepsin B |
| Primary Target IC<sub>50</sub> | 2.24 nM against cathepsin B |
| Purity | ≥98% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
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| Specifications |
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| Número de catálogo | GTIN |
| 205531-1MG | 07790788048433 |
Documentation
CA-074 Me - Calbiochem MSDS
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CA-074 Me - Calbiochem Certificados de análise
| Título | Número do lote |
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| 205531 |
Referências
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| Sever, N., et al. 2002. Biol. Chem. 383, 839. Authier, F., et al. 1999. J. Biol. Chem. 274, 33723. Hill, P.A., et al. 1994. J. Cell Biochem. 56, 118. Buttle, D.J., et al. 1992. Arch. Biochem. Biophys. 299, 377. |
Citações
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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