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ABN648 Anti-TRESK Antibody

Anti-TRESK Antibody is an antibody against TRESK for use in western blotting, IHC & immunofluorescence.

Anti-TRESK Antibody: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: KCNK18, TRESK, TRIK UniProt Number: Q7Z418
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ABN648
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      RWB, IHC, IFRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN648
      DescriptionAnti-TRESK Antibody
      Alternate Names
      • Potassium channel subfamily K member 18
      • TWIK-related individual potassium channel
      • TWIK-related spinal cord potassium channel
      Background InformationPotassium channel subfamily K member 18, also known as TWIK-related individual potassium channel or TWIK-related spinal cord potassium channel, and encoded by the gene name KCNK18 or TRESK or TRIK, is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic Tlymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction. Mutations in TRESK have been assoicated with migraine with or without aura 13.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality SegmentMQ100
      Applications
      ApplicationAnti-TRESK Antibody is an antibody against TRESK for use in western blotting, IHC & immunofluorescence.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      • Immunofluorescence
      Application NotesImmunohistochemistry Analysis: 5 μg/mL from a representative lot detected TRESK in rat brain tissue.

      Immunofluorescence Analysis: 20 μg/mL from a representative lot detected TRESK in rat brain cells.
      Biological Information
      ImmunogenKLH-conjugated synthetic peptide corresponding to the center region of human TRESK.
      Epitopecenter region
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Rat
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • KCNK18
      • TRESK
      • TRIK
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~40 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Rat brain tissue lysate.

      Western Blotting Analysis: 2 μg/mL of this antibody detected TRESK in Rat brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade ITEM Number
      Bestellnummer GTIN
      ABN648 04053252946691