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AB9830-200UL Anti-K2P4.1 Antibody

This Anti-K2P4.1 Antibody is validated for use in IH, WB for the detection of K2P4.1.

Anti-K2P4.1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Ion Channels & Transporters Gene Symbol: KCNK4, TRAAK, K2p4.1, TRAAK1 UniProt Number: Q9NYG8
AB9830-200UL
200 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      RIHC, WBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB9830-200UL
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-K2P4.1 Antibody
      Alternate Names
      • TRAAK
      • TWIK-related arachidonic acid-stimulated K+ channel
      • KCNK4
      References
      Product Information
      FormatAffinity Purified
      Control
      • Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 μL of sterile deionized water. For negative control, preincubate 1 μg of peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
      PresentationAffinity purified immunoglobulin. Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.025% sodium azide as a preservative. Reconstitute with 200 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).
      Quality SegmentMQ100
      Applications
      ApplicationThis Anti-K2P4.1 Antibody is validated for use in IH, WB for the detection of K2P4.1.
      Key Applications
      • Immunohistochemistry
      • Western Blotting
      Application NotesWestern blot: 1:200 using ECL on rat cerebellum lysate and HEK- K2P4.1 transfected cells.

      Immunohistochemistry on rat brain sections.

      Dilutions should be made using a carrier protein such as BSA (1-3%).

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenPurified peptide from amino acids 343-359 of human K2P4.1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes K2P4.1 (TRAAK, TWIK-related arachidonic acid-stimulated K+ channel, KCNK4).
      IsotypeIgG
      Species Reactivity
      • Rat
      Species Reactivity NoteThe immunogen sequence is identical in mouse, rat and canine.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryPotassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids.
      Gene Symbol
      • KCNK4
      • TRAAK
      • K2p4.1
      • TRAAK1
      Purification MethodImmunoAffinity Purified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q9NYG8 # Voltage insensitive, instantaneous, outwardly rectifying potassium channel. Outward rectification is reversed at high external K(+) concentrations (By similarity).
      SIZE: 393 amino acids; 42704 Da
      SUBUNIT: Homodimer (Potential).
      SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).
      SIMILARITY: SwissProt: Q9NYG8 ## Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size200 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade ITEM Number
      Catalogue Number GTIN
      AB9830-200UL 04053252402647

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies