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ABS224 Anti-YVH1 Antibody

Anti-YVH1 Antibody is an antibody against YVH1 for use in Western Blotting.

Anti-YVH1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Kinases & Phosphatases Gene Symbol: DUSP12 UniProt Number: Q9UNI6
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ABS224
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABS224
DescriptionAnti-YVH1 Antibody
Alternate Names
  • Dual specificity protein phosphatase 12
  • Dual specificity tyrosine phosphatase YVH1
Background InformationYeast VH1-related phosphatase (YVH1), also known as “dual specificity protein phosphatase 12” (DUSP12) is a ubiquitous phosphatase, with relatively high levels of expression in the ovary, testis, spleen, and peripheral blood leukocytes. YVH1 primarily removes phosphate groups from phosphorylated serine, threonine, and tyrosine residues in its target substrates. However, YVH1 also contains a zinc-binding domain which may enable it to interact with other proteins involved in cell growth, cell survival, and cell cycle progression. YVH1 may also be involved in the assembly of ribosomes, and in the biogenesis of the 60S ribosomal subunit. It can be targeted to different subcellular locations by phosphorylation of its Ser335 residue located in the zinc-binding domain.
References
Product Information
FormatAffinity Purified
Control
  • HeLa cells
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality SegmentMQ100
Applications
ApplicationAnti-YVH1 Antibody is an antibody against YVH1 for use in Western Blotting.
Key Applications
  • Western Blotting
Application NotesWestern Blot Analysis: A representative lot detected YVH1 in 10 µg of Jurkat cell lysate.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human YVH1.
HostRabbit
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • DUSP12
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~38 kDa observed. An uncharacterized band at ~36 kDa may be observed in some cell lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in HeLa cells.

Western Blot Analysis: A 1:500 dilution of this antibody detected YVH1 in 10 µg of HeLa cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade ITEM Number
Catalogue Number GTIN
ABS224 04053252522758