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ABC925 Anti-AMACR Antibody

Anti-AMACR Antibody is an antibody against AMACR for use in Western Blotting and Immunohistochemistry.

Anti-AMACR Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: AMACR UniProt Number: Q9UHK6
ABC925
100 µg  
Purchase on Sigma-Aldrich

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概述

Replacement Information

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重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC925
DescriptionAnti-AMACR Antibody
Alternate Names
  • AMACR
  • Alpha-methylacyl-CoA racemase
  • 2-methylacyl-CoA racemase
Background InformationAlpha-methylacyl-CoA racemase is encoded by the AMACR gene and catalyzes the convertion of various (2R)-methylacyl-CoA esters to the corresponding (2S)-methylacyl-CoA epimers. AMACR deficiency (AMACRD) is a rare autosomal recessive peroxisomal disorder characterized by elevated plasma concentrations of pristanic acid C27-bile-acid intermediates, resulting in variable neurodegenerative symptoms affecting the central and peripheral nervous systems, including seizures, visual failure, sensorimotor neuropathy, spasticity, migraine, and white matter hyperintensities on brain imaging.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality SegmentMQ300
Applications
ApplicationAnti-AMACR Antibody is an antibody against AMACR for use in Western Blotting and Immunohistochemistry.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected AMACR in human kidney tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human AMACR near the N-terminal.
EpitopeNear N-terminal
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
Species Reactivity NoteHuman. Predicted to react with Baboon, Monkey, Bovine based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • AMACR
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~43 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human kidney tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected AMACR in 10 µg of human kidney tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade ITEM Number
产品目录编号 GTIN
ABC925 04055977137088