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AB3274-200UL Anti-Aquaporin 2 Antibody

Anti-Aquaporin 2 Antibody is an antibody against Aquaporin 2 for use in WB, IH.

Anti-Aquaporin 2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Ion Channels & Transporters Gene Symbol: AQP2, AQP-CD, aquaporin-CD, Aquaporin-2, Aquaporin-CD, AQP-2, MGC34501, WCH-CD UniProt Number: P41181
AB3274-200UL
200 µL  
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概述

Replacement Information

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重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, RWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB3274-200UL
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Aquaporin 2 Antibody
Alternate Names
  • AQP2
  • AQP-CD
  • WCD-CD
References
Product Information
FormatAffinity Purified
Control
  • Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). Reconstitute with 100 μL of deionized water. For negative control, preincubate 0.5ug of purified peptide with 1 μg of antibody for one hour at room temperature.

    Optimal concentrations must be determined by the end user.
PresentationAffinity purified immunoglobulin. Lyophilized from PBS, pH 7.4, containing 1% BSA and 0.05% sodium azide. Reconstitute with 200 μL of sterile distilled water. Centrifuge antibody preparation before use (10,000 x g for 5 min).
Quality SegmentMQ100
Applications
ApplicationAnti-Aquaporin 2 Antibody is an antibody against Aquaporin 2 for use in WB, IH.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesWestern blotting: 1:200-1:1000 using ECL on rat kidney membranes.

Immunohistochemistry on rat kidney sections.

Dilutions should be made using a carrier protein such as BSA (1-3%).

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenHighly purified peptide corresponding to residues 254-271 of rat or mouse Aquaporin 2 (SwissProt accession number P34080).
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityRecognizes Aquaporin 2.

SPECIES REACTIVITIES: The epitope specific for Aquaporin 2 is identical in rat and mouse and only slightly different in human (17/18 amino acids). Reactivity with other species has not yet been tested.
Species Reactivity
  • Human
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThis gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant, and recessive forms of nephrogenic diabetes insipidus.
Gene Symbol
  • AQP2
  • AQP-CD
  • aquaporin-CD
  • Aquaporin-2
  • Aquaporin-CD
  • AQP-2
  • MGC34501
  • WCH-CD
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P41181 # Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
SIZE: 271 amino acids; 28837 Da
SUBCELLULAR LOCATION: Apical cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Shuttles from vesicles to the apical membrane.
TISSUE SPECIFICITY: Expressed in renal collecting tubules.
DOMAIN: SwissProt: P41181 Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
PTM: Ser-256 phosphorylation is necessary and sufficient for expression at the apical membrane. Endocytosis is not phosphorylation-dependent.
DISEASE:SwissProt: P41181 # Defects in AQP2 are a cause of autosomal nephrogenic diabetes insipidus, type I (AD-NDI) [MIM:125800]. It is characterized by excessive water drinking (polydypsia) and urine excretion (polyuria).
SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain lyophilized material at -20°C for up to 6 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size200 µL
Transport Information
Supplemental Information
Specifications
Global Trade ITEM Number
产品目录编号 GTIN
AB3274-200UL 04053252508394

Documentation

Anti-Aquaporin 2 Antibody MSDS

职位

物料安全数据表 (MSDS) 

Anti-Aquaporin 2 Antibody 分析证书

标题批号
RABBIT ANTI-AQUAPORIN 2 (AQP2, AQP-CD, WCH-CD) POLYCLONAL ANTIBODY - 2122410 2122410
RABBIT ANTI-AQUAPORIN 2 (AQP2, AQP-CD, WCH-CD) - 2492114 2492114
RABBIT ANTI-AQUAPORIN 2 (AQP2, AQP-CD, WCH-CD) - 3243552 3243552
RABBIT ANTI-AQUAPORIN 2 (AQP2, AQP-CD, WCH-CD) - 3410076 3410076
RABBIT ANTI-AQUAPORIN 2 (AQP2, AQP-CD, WCH-CD) - 3490857 3490857
RABBIT ANTI-AQUAPORIN 2 (AQP2, AQP-CD, WCH-CD) POLYCLONAL ANTIBODY 3095007
RABBIT ANTI-AQUAPORIN 2 (AQP2, AQP-CD, WCH-CD) POLYCLONAL ANTIBODY -
RABBIT ANTI-AQUAPORIN 2 (AQP2, AQP-CD, WCH-CD) POLYCLONAL ANTIBODY - 2187353 2187353
RABBIT ANTI-AQUAPORIN 2 (AQP2, AQP-CD, WCH-CD) POLYCLONAL ANTIBODY - 2365521 2365521
RABBIT ANTI-AQUAPORIN 2 - 2556276 2556276
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数据表

标题
RABBIT ANTI-AQUAPORIN 1 POLYCLONAL ANTIBODY