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AB15076 Anti-Ephrin Receptor B2 Antibody

Anti-Ephrin Receptor B2 Antibody detects level of Ephrin Receptor B2 & has been published & validated for use in WB.

Anti-Ephrin Receptor B2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Growth Cones & Axon Guidance Gene Symbol: EPHB2, EphB2, CAPB, EPHT3, Hek5, DRT, EPTH3, TYRO5, ERK, HEK5, MGC87492, PCBC, Tyro5 UniProt Number: P29323
AB15076
100 µg  
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重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
RWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB15076
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Ephrin Receptor B2 Antibody
References
Product Information
FormatAffinity Purified
PresentationLiquid in PBS with 0.1% sodium azide.
Applications
ApplicationAnti-Ephrin Receptor B2 Antibody detects level of Ephrin Receptor B2 & has been published & validated for use in WB.
Key Applications
  • Western Blotting
Application NotesWestern blot: 1:500-1:2,000 on adult rat brain lysate.

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenSynthetic peptide.
HostRabbit
SpecificityEphrin Receptor B2. By Western blot the antibody recognizes a doublet band at ~90-118 kDa in adult rat brain lysate.
Species Reactivity
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryEphrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
Gene Symbol
  • EPHB2
  • EphB2
  • CAPB
  • EPHT3
  • Hek5
  • DRT
  • EPTH3
  • TYRO5
  • ERK
  • HEK5
  • MGC87492
  • PCBC
  • Tyro5
Purification MethodImmunoAffinity Purified
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P29323 # Receptor for members of the ephrin-B family. Acts as a tumor suppressor.
SIZE: 1055 amino acids; 117493 Da
SUBUNIT: The ligand-activated form interacts with multiple proteins, including GTPase-activating protein (RASGAP) through its SH2 domain. Binds RASGAP through the juxtamembrane tyrosines residues. Interacts with PRKCABP and GRIP1 (By similarity).
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. Preferentially expressed in fetal brain.
DISEASE:SwissProt: P29323 # Defects in EPHB2 are involved in the progression of prostate cancer [MIM:176807]. & Defects in EPHB2 are involved in the development of prostate cancer metastasis to the brain [MIM:603688].
SIMILARITY: SwissProt: P29323 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. & Contains 2 fibronectin type-III domains. & Contains 1 protein kinase domain. & Contains 1 SAM (sterile alpha motif) domain.
Molecular Weight~90-118kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade ITEM Number
产品目录编号 GTIN
AB15076 04053252730320