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AB3371-I Anti-Resistin

Anti-Resistin Antibody, Cat. No. AB3371-I, is a rabbit polyclonal antibody that detects rat resistin and has been tested for use in Western Blotting.

Anti-Resistin MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Gene Symbol: RETN, FIZZ3, HXCP1, RSTN UniProt Number: Q9HD89
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AB3371-I
100 µL  
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概述

Replacement Information

重要规格表

Species ReactivityKey ApplicationsHostFormatAntibody Type
RWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB3371-I
DescriptionAnti-Resistin
Alternate Names
  • Adipose tissue-specific secretory factor
  • ADSF
  • C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein
  • Cysteine-rich secreted protein A12-alpha-like 2
  • Cysteine-rich secreted protein FIZZ3
Background InformationResistin (UniProt: Q9HD89; also known as Adipose tissue-specific secretory factor, ADSF,C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3) is encoded by the RETN (also known as FIZZ3, HXCP1, RSTN) gene (Gene ID: 56729) in rat. Resistin is a dilsulfide-linked homodimeric hormone secreted by the white adipose tissue. It is widely expressed, with strong expression in lung, bone marrow, and breast tissue. Resistin (resistance to insulin) was originally named for its ability to resist or interfere with the action of insulin. It has been linked to the development of atherosclerosis and cardiovascular diseases, non-alcoholic fatty liver disease, rheumatic disease, malignancy, asthma, inflammatory bowel disease and chronic kidney disease. It suppresses the ability of insulin to stimulate glucose uptake into adipose cells and is a key molecule linking obesity to diabetes. Circulating resistin levels are shown to be elevated in diet-induced and genetic forms of obesity and administration of anti-resistin antibody is shown to improve blood glucose levels and insulin action in mice with diet-induced obesity. Two isoforms of resistin have been described that are generated by alternative splicing. (Ref.: Jamaluddin MS et al (2012). Br J Pharmacol. 165(3); 622-632; Steppan, CM et al. (2001). Nature 409 (6818); 307-312).
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality SegmentMQ100
Applications
ApplicationAnti-Resistin Antibody, Cat. No. AB3371-I, is a rabbit polyclonal antibody that detects rat resistin and has been tested for use in Western Blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to 17 amino acids from the N-terminal region of rat resistin.
EpitopeN-terminus
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
SpecificityThis rabbit polyclonal antibody detects Resistin in rat tissues. It targets an epitope within 17 amino acids from the N-terminal region.
Species Reactivity
  • Rat
Species Reactivity NoteRat.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • RETN
  • FIZZ3
  • HXCP1
  • RSTN
Purification MethodAffinity Purified
UniProt Number
Molecular Weight~12 kDa observed; 11.42 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in Resistin Recombinant Protein.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected recombinant rat resistin.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade ITEM Number
产品目录编号 GTIN
AB3371-I 04054839370014