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525185 Phospholipase C Activator, m-3M3FBS - CAS 200933-14-8 - Calbiochem

The Phospholipase C Activator, m-3M3FBS, also referenced under CAS 200933-14-8, controls the biological activity of Phospholipase C. This small molecule/inhibitor is primarily used for Activators/Inducers applications.

Phospholipase C Activator, m-3M3FBS - CAS 200933-14-8 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

同义词: m-3M3FBS, 2,4,6-Trimethyl-N-(m-3-trifluoromethylphenyl)benzenesulfonamide

Primary Target: Phospholipase C (PLC)
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概述

Replacement Information

重要规格表

CAS #Empirical Formula
200933-14-8C₁₆H₁₆F₃NO₂S

Products

产品目录编号包装 数量 / 包装
525185-10MGCN 塑胶安瓿;塑胶针药瓶 10 mg
Description
OverviewA novel sulfonamide compound that acts as a cell-permeable and specific activator of phospholipase C (PLC). Shown to stimulate the PLC-mediated intracellular Ca2+ release, inositol phosphates production, and superoxide generation in various cell types. It activates all PLC isotypes (β2, β3, γ1, γ2, and δ1) in vitro, but not heterotrimeric G proteins, PI 3-kinase, or PLD.
Catalogue Number525185
Brand Family Calbiochem®
Synonymsm-3M3FBS, 2,4,6-Trimethyl-N-(m-3-trifluoromethylphenyl)benzenesulfonamide
References
ReferencesBae, Y.S., et al. 2003. Mol. Pharmacol. 63, 1043.
Product Information
CAS number200933-14-8
ATP CompetitiveN
FormOff-white solid
Hill FormulaC₁₆H₁₆F₃NO₂S
Chemical formulaC₁₆H₁₆F₃NO₂S
HS Code3507 90 49
ReversibleN
Structure formula ImageStructure formula Image
Quality SegmentMQ100
Applications
Biological Information
Primary TargetPhospholipase C (PLC)
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Carcinogenic / Teratogenic
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade ITEM Number
产品目录编号 GTIN
525185-10MGCN 04055977197150

Documentation

Phospholipase C Activator, m-3M3FBS - CAS 200933-14-8 - Calbiochem MSDS

职位

物料安全数据表 (MSDS) 

Phospholipase C Activator, m-3M3FBS - CAS 200933-14-8 - Calbiochem 分析证书

标题批号
525185

参考

参考信息概述
Bae, Y.S., et al. 2003. Mol. Pharmacol. 63, 1043.

引用

标题
  • Eva Mortier, et al. (2005) Nuclear speckles and nucleoli targeting by PIP2-PDZ domain interactions. The EMBO Journal 24, 2556-2565.
    		•
    数据表

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision26-August-2008 RFH
    Synonymsm-3M3FBS, 2,4,6-Trimethyl-N-(m-3-trifluoromethylphenyl)benzenesulfonamide
    DescriptionA cell-permeable and specific activator of phospholipase C (PLC). Reported to stimulate PLC-mediated intracellular Ca2+ release, inositol phosphate production, and superoxide generation in various cell types. Activates all PLC isotypes (β2, β3, γ1, &gamma2, and δ1) in vitro, but does not exhibit any effect on heterotrimeric G proteins, PI 3-kinase, or phospholipase D.
    FormOff-white solid
    Intert gas (Yes/No) Packaged under inert gas
    CAS number200933-14-8
    Chemical formulaC₁₆H₁₆F₃NO₂S
    Structure formulaStructure formula
    Purity≥95% by HPLC
    SolubilityDMSO (7 mg/ml)
    Storage Protect from light
    +2°C to +8°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.
    Toxicity Carcinogenic / Teratogenic
    ReferencesBae, Y.S., et al. 2003. Mol. Pharmacol. 63, 1043.
    Citation
  • Eva Mortier, et al. (2005) Nuclear speckles and nucleoli targeting by PIP2-PDZ domain interactions. The EMBO Journal 24, 2556-2565.
    		•