A8185
Ala-Gln
BioReagent, suitable for cell culture, suitable for insect cell culture
Synonym(s):
Alanyl-glutamine, Glutamine-S
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About This Item
Empirical Formula (Hill Notation):
C8H15N3O4
CAS Number:
Molecular Weight:
217.22
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.75
product line
BioReagent
Quality Segment
assay
≥98% (HPLC)
form
powder
technique(s)
cell culture | insect: suitable, cell culture | mammalian: suitable
color
white to off-white
storage temp.
room temp
SMILES string
NC(CC[C@H](NC([C@@H](N)C)=O)C(O)=O)=O
InChI
1S/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H,2-3,9H2,1H3,(H2,10,12)(H,11,13)(H,14,15)/t4-,5-/m0/s1
InChI key
HJCMDXDYPOUFDY-WHFBIAKZSA-N
Application
Ala-Gln has been used:
- as a supplement in NeuralQ™ medium
- as a component in growth medium and incubation medium (IM) for retinal cell lines
- for experimental treatment of retinal cell lines respectively
Biochem/physiol Actions
Alanyl-glutamine (Ala-Gln) is a dipeptide that is used as a substitute for glutamine in mammalian cell culture media, because of the instability of glutamine in solution and the formation of ammonia as a breakdown product of glutamine in solution, which can have deleterious effects on cells in culture. Ala-Glu is stable to heat sterilization and is less ammonia genic than glutamine, which contributes to its advantages as a media component. Ala-Gln has been utilized to investigate polymorphonuclear leucocyte and myeloperoxidase activity in vitro.
Analysis Note
This product is cell culture tested (0.5 mg/ml) and insect cell culture tested (0.2 mg/ml). It is appropriate for use in cell culture and insect cell culture applications at 2-10 mM.
Legal Information
NeuralQ is a trademark of GlobalStem
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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