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P3032

Penicillin G sodium salt

Name: Penicillin G sodium salt
Brand: SIGMA

powder, suitable for cell culture, BioReagent

Synonym(s):

Benzylpenicillin sodium salt

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About This Item

Empirical Formula (Hill Notation):

C₁₆H₁₇N₂NaO₄S

CAS Number:

69-57-8

Molecular Weight:

356.37

NACRES:

NA.76

PubChem Substance ID:

24898384

eCl@ss:

34010400

UNSPSC Code:

12352207

EC Number:

200-710-2

MDL number:

MFCD00069666

Beilstein/REAXYS Number:

3834217

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Properties

Product Name

Penicillin G sodium salt, powder, BioReagent, suitable for cell culture

product line

BioReagent

Quality Segment

200

form

powder

potency

≥1477 units per mg

technique(s)

cell culture | mammalian: suitable

solubility

H₂O: 100 mg/mL

antibiotic activity spectrum

Gram-positive bacteria

mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

SMILES string

[Na+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O

InChI

1S/C16H18N2O4S.Na/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

InChI key

FCPVYOBCFFNJFS-LQDWTQKMSA-M

Description

General description

Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for extended periods. Solutions are stable at 37°C for 3 days.

Chemical structure: β-lactam

Application

Penicillin G is a narrow spectrum natural antibiotic. It is effective against Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. It has been used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility and in cell culture both alone and combined with streptomycin and other antibiotics.

Biochem/physiol Actions

Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.

Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.

Other Notes

1mu,10mu,25mu,100mu

Keep container tightly closed in a dry and well-ventilated place.Product contains Penicillin Keep in a dry place.

Disclaimer

Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The sodium salt is soluble in H₂O at 100 mg/mL.