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14-926M IKKε Protein, active, 250 µg

Active, N-terminal FLAG & GST-tagged, recombinant, human IKKε, full length. For use in Kinase Assays.

IKKε Protein, active, 250 µg: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
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14-926M
250 µg  Also available in 10μg size as catalog # 14-926 and in bulk as catalog # 14-926-K.
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      Übersicht

      Replacement Information
      Description
      Catalogue Number14-926M
      Trade Name
      • Upstate
      DescriptionIKKε Protein, active, 250 µg
      OverviewIKBKE is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. May play a special role in the immune response. Protects cells against DNA damage-induced cell death.
      References
      Product Information
      Presentation50mM Tris/HCl pH7.5, 150mM NaCl, 10mM β-glycerophosphate, 1mM sodium orthovanadate, 1mM NaF, 28% v/v glycerol, 0.03% Brij-35, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol
      Quality SegmentMQ300
      Applications
      ApplicationActive, N-terminal FLAG & GST-tagged, recombinant, human IKKε, full length. For use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      SourceN-terminal FLAG and GST-tagged, recombinant, human IKK full length, expressed by baculovirus in Sf21 insect cells.
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Gene Symbol
      • IKBKE
      • IKKe
      • IKKI
      • KIAA0151
      Protein TargetIKKe
      Purification MethodPurified by immunoaffinity chromatography.
      Target Sub-FamilyMisc
      UniProt Number
      Molecular Weight109 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of casein.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10μg size as catalog # 14-926 and in bulk as catalog # 14-926-K.
      Transport Information
      Supplemental Information
      Specifications
      Global Trade ITEM Number
      Bestellnummer GTIN
      14-926M 04053252851452

      Verwandte Produkte & Anwendungen

      Alternative Packsize

      Bestellnummer Beschreibung  
      14-926 IKKε Protein, active, 10 µg Preis & Verfügbarkeit

      Produktfamilien

      Kinase & Phosphatase Products

      Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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      Kategorien

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases