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539610 PKCζ/ι Pseudosubstrate Inhibitor - Calbiochem

The PKCζ/ι Pseudosubstrate Inhibitor controls the biological activity of PKCζ/ι. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

PKCζ/ι Pseudosubstrate Inhibitor - Calbiochem : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.

Synonymes: SIYRRGARRWRKL, Protein Kinase Cζ/ι Pseudosubstrate Inhibitor

Primary Target: PKCζ
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539610
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Aperçu

Replacement Information

Tableau de caractéristiques principal

Empirical Formula
C₇₆H₁₂₈N₃₀O₁₆

Prix & Disponibilité

Référence DisponibilitéConditionnement Qté Prix Quantité
539610-500UG
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      		 Ampoule plast. 500 μg
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      Description
      OverviewA selective, reversible, and substrate competitive inhibitor of protein kinase Cζ and protein kinase Cι (PKCζ/ι) isozymes.
      Catalogue Number539610
      Brand Family Calbiochem®
      SynonymsSIYRRGARRWRKL, Protein Kinase Cζ/ι Pseudosubstrate Inhibitor
      References
      ReferencesSajan, M.P., et al. 1999. J. Biol. Chem. 274, 30495.
      Laudanna, C., et al. 1998. J. Biol. Chem. 273, 30306.
      Standaert, M.L., et al. 1997. J. Biol. Chem. 272, 30075.
      Product Information
      ATP CompetitiveN
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₇₆H₁₂₈N₃₀O₁₆
      Chemical formulaC₇₆H₁₂₈N₃₀O₁₆
      Hygroscopic Hygroscopic
      ReversibleY
      Quality SegmentMQ100
      Applications
      Biological Information
      Primary TargetPKCζ
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceH-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade ITEM Number
      Référence GTIN
      539610-500UG 04055977194777

      Documentation

      PKCζ/ι Pseudosubstrate Inhibitor - Calbiochem FDS

      Titre

      Fiche de données de sécurité des matériaux (FDS) 

      PKCζ/ι Pseudosubstrate Inhibitor - Calbiochem Certificats d'analyse

      TitreNuméro de lot
      539610

      Références bibliographiques

      Aperçu de la référence bibliographique
      Sajan, M.P., et al. 1999. J. Biol. Chem. 274, 30495.
      Laudanna, C., et al. 1998. J. Biol. Chem. 273, 30306.
      Standaert, M.L., et al. 1997. J. Biol. Chem. 272, 30075.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-January-2010 RFH
      SynonymsSIYRRGARRWRKL, Protein Kinase Cζ/ι Pseudosubstrate Inhibitor
      DescriptionNon-cell-permeable protein kinase Cζ and protein kinase Cι pseudosubstrate sequence peptide that can be used as a selective, reversible, and substrate competitive inhibitor PKCζ/ι in in vitro kinase assays.
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Recommended reaction conditions
      PKCζ or PKCι -containing sample is incubated at 30-37°C, with or without 400 µM PKCζ/ι pseudosubstrate inhibitor, in 50 mM Tris-HCl buffer (pH 7.5) containing 5 mM MgCl2, 100 µM Na3VO4, 100 µM Na4P2O7, 1 mM NaF, 100 µM PMSF, 50 µM ATP, 5 µCi [γ-32P]ATP, 4 µg phosphatidylserine, and 40 µM PKCζ/ι substrate (Cat. No. 539667).
      Chemical formulaC₇₆H₁₂₈N₃₀O₁₆
      Peptide SequenceH-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-OH
      Purity≥95% by HPLC
      SolubilityGlacial acetic acid (2 mg/ml) or H₂O (2 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesSajan, M.P., et al. 1999. J. Biol. Chem. 274, 30495.
      Laudanna, C., et al. 1998. J. Biol. Chem. 273, 30306.
      Standaert, M.L., et al. 1997. J. Biol. Chem. 272, 30075.