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AB15301 Anti-RanBPM Antibody

Anti-RanBPM Antibody is an antibody against RanBPM for use in WB, IH.

Anti-RanBPM Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Growth Cones & Axon Guidance Gene Symbol: MPP8, MPHOSPH8, TWA3 UniProt Number: Q99549
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AB15301
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, H, RWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB15301
      Trade Name
      • Chemicon
      DescriptionAnti-RanBPM Antibody
      Background InformationRanBPM is shown to physically interact with Plexin-A1, and the RanBPM/Plexin complex is regulated by MICAL expression. Overexpression of RanBPM cooperates with PlexinA1 to reduce non-neuronal cell spreading and strongly inhibit axonal outgrowth in vitro and in vivo. A truncated RanBPM protein blocks Sema3A responsiveness in non-neuronal and neuronal cells. Suppression of RanBPM expression reduces Sema3A responsiveness. Thus, RanBPM is a mediator of Sema3A signaling through Plexin-A. RanBPM has the potential to link Plexin-A receptors to retrograde transport and microtubule function in axonal guidance
      References
      Product Information
      FormatAffinity Purified
      Control
      • Tested on mouse, rat and human brain
      PresentationPurified Antibody in PBS with 0.1% NaN3
      Quality SegmentMQ100
      Applications
      ApplicationAnti-RanBPM Antibody is an antibody against RanBPM for use in WB, IH.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern blot Analysis: RanBPM can be detected at 1/1000 in rat, mouse and human brain

      Immunohistochemistry: 1:50 and 1:500 dilution of Cat. # AB15301 was tested on human normal, tumor tissue and tonsil tissue.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic Peptide
      HostRabbit
      SpecificityRanBPM
      Species Reactivity
      • Mouse
      • Human
      • Rat
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • MPP8
      • MPHOSPH8
      • TWA3
      Purification MethodImmunoAffinity Purified
      UniProt Number
      Molecular Weight71 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade ITEM Number
      Catalogue Number GTIN
      AB15301 04053252373336