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137042 KRISTAL TRI-SODIUM SITRAT DIHIDRAT

EMPROVE® EXPERT Ph Eur,BP,JP,USP,ACS

KRISTAL TRI-SODIUM SITRAT DIHIDRAT MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Trisodium Citrate, Sodium Citrate, Dihydrate

CAS #: 6132-04-3 EC Number: 200-675-3 Molar Mass: 294.10 g/mol Hill Formula: C₆H₅Na₃O₇ * 2 H₂O Grade: Ph Eur,BP,JP,USP,ACS
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Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
6132-04-3200-675-3C₆H₅Na₃O₇ * 2 H₂O294.10 g/molPh Eur,BP,JP,USP,ACS
Description
Catalogue Number137042
SynonymsTrisodium Citrate, Sodium Citrate, Dihydrate
References
Product Information
CAS number6132-04-3
EC number200-675-3
GradePh Eur,BP,JP,USP,ACS
Hill FormulaC₆H₅Na₃O₇ * 2 H₂O
Molar Mass294.10 g/mol
HS Code2918 15 00
Structure formula ImageStructure formula Image
Quality SegmentMQ500
Applications
Biological Information
Physicochemical Information
Melting Point300 °C (senyawa anhydrat)
pH value7.5 - 9.0 (50 g/l, H₂O, 25 °C)
Bulk density600 kg/m3
Solubility720 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Tikus > 8000 mg/kg
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDKein Gefahrgut
Declaration (transport by air) IATA-DGRNo Dangerous Good
Declaration (transport by sea) IMDG-CodeNo Dangerous Good
Supplemental Information
Specifications
Assay (Perchloric acid titration, calc. on anhydrous substance (Ph Eur))99.0 - 101.0 %
Assay (Perchloric acid titration, previously dried substance) (JP/USP)99.0 - 100.5 %
Identity (Na)passes test
Identity (Citrate)passes test
Identity (reaction upon ignition)passes test
Appearancewhite crystals
Appearance of solution (100 g/l, CO₂-free water)clear and colorless
Acidity or alkalinitypasses test
pH (50 g/l CO₂-free water)7.5 - 8.5
In water insoluble matter #≤ 50 ppm
Chloride (Cl)≤ 30 ppm
Sulfate (SO₄)≤ 50 ppm
Heavy metals (as Pb)≤ 5 ppm
Al (Aluminium)≤ 5 ppm
As (Arsenic)≤ 2 ppm
NH4 (Ammonium) #≤ 30 ppm
Ca (Calcium) #≤ 50 ppm
Fe (Iron) #≤ 5 ppm
Oxalate (as C₂H₂O₄)≤ 300 ppm
Tartrate (C₄H₄O₆)passes test
Residual solvents (ICH (Q3C))excluded by manufacturing process
Readily carbonisable substancepasses test
Water (according to Karl Fischer)11.0 - 13.0 %
Loss on drying (180 °C, 18 h)10.0 - 13.0 %
Total aerobic microbial count (TAMC)≤ 100 CFU/g
Total combined yeasts/moulds count (TYMC)≤ 10 CFU/g
Bile-tolerant gram-negative bacteria (absent in 1 g)passes test
Candida albicans (absent in 1 g)passes test
Escherichia coli (absent in 1 g)passes test
Pseudomonas aeruginosa (absent in 1 g)passes test
Salmonella (absent in 10 g)passes test
Staphylococcus aureus (absent in 1 g)passes test
Bacterial endotoxins≤ 2.5 I.U./g
# Additional requirements by ACS
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., BP, JP, USP, ACS

Documentation

Quality Management Dossier (Open Access)

Title

KRISTAL TRI-SODIUM SITRAT DIHIDRAT MSDS

Title

Safety Data Sheet (SDS) 

KRISTAL TRI-SODIUM SITRAT DIHIDRAT Certificates of Analysis

Product Number PackagingLot Number
137042

Certificates

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