Targeted Protein Degradation Partners
WEBINAR
Targeted Protein Degradation (TPD) has created a paradigm shift and emerged as a front-runner in drugging many "undruggable" targets. As a new modality, it poses unique challenges for lead discovery as well as API development and manufacturing.
We will focus on the latest advances in chemical building blocks for protein degradation, including warheads, linkers, and ligands, and how they can be used to build better degraders. Once a candidate has been identified, selection of the right CDMO can take a phase-appropriate approach to develop with commercial readiness in mind, provide partnered quality and regulatory support, and offer batch scalability as you progress through the clinic.
In this webinar, you will learn about:
- Targeted Protein Degradation (TPD) technologies
- A mechanistic view of this new modality
- Chemical advancements for modular and strategic degrader design
- How to select the appropriate contract manufacturing partner
Pharma and biopharma manufacturing
- Detecting & Removing Aggregates
Duration:1h
Language:English
Session 1:presented June 15, 2023