More Success in LC-MS – Tips and Tricks for Sample & Mobile Phase Preparation and Column Selection

WEBINAR

What Does It Cover?

LC-MS is one of the most commonly used analytical techniques in various sectors for quantitation and identification of unknown from variety of complex samples. Use of LC-MS has expanded over the years as it offers both selectivity and specificity in analysis. With advances in both chromatography and mass spectrometry, sensitivity and accuracy of this technique has further increased, allowing for detection and identification of low-level analytes in complex sample matrices.

The LC-MS workflow has three main components, which determine successful analyses: sample preparation, choice of mobile phase components and column selection. Not paying enough attention to one of these components can complicate data analysis, quantitation and identification.

In this seminar, you will learn critical factors to consider when selecting the sample preparation methods, mobile phase components and HPLC columns.

What Will You Learn?

We will discuss:

• Different sample preparation methods and their effect on sample clean up (particle removal, analyte binding, and extractables)
  • Quality of mobile phase components (solvents, water and buffer salts) and their impact on background signal in LC-MS analysis
  • HPLC column selection
  • Useful tips to improve overall chromatography performance

Who Should Attend?

Scientists, technicians, PIs who use LC-MS and HPLC in drug development, pharmaceutical, proteomics, food analysis, environmental applications.