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About This Item
UNSPSC Code:
12161503
NACRES:
NA.84
Input:
sample type serum
sample type plasma (K2 EDTA)
sample type plasma (K2 EDTA)
Species reactivity:
canine
Storage temp.:
2-8°C
Shipped in:
wet ice
Product Name
Canine Leptin ELISA,
species reactivity
canine
Quality Segment
packaging
kit of 1 × 96 wells
parameter
20 μL sample volume (4hr assay)
technique(s)
ELISA: suitable
input
sample type serum
sample type plasma (K2 EDTA)
application(s)
research use
assay range
inter-assay cv: 6-7%
intra-assay cv: 2-6%
sensitivity: 0.21 ng/mL
standard curve range: 0.78-50 ng/mL
accuracy: 100-106%
detection method
colorimetric (450nm/590nm)
shipped in
wet ice
storage temp.
2-8°C
General description
Leptin, a 16 kD protein and a product of the obesity (ob) gene, is synthesized and secreted predominantly by adipose tissue and is, therefore, considered an adipokine. With circulating levels directly proportional to the total amount of body fat, leptin plays an important role in whole body metabolism, regulating food intake and energy balance, as well as assisting in the control of homeostasis, reproductive function, the immune system and numerous other body functions. Binding to receptors of the hypothalamus, leptin signals food satiety and reduces appetite, although evidence suggests that, in general, obese people may have unusually high circulating levels of leptin. This may indicate a resistance to leptin similar to the insensitivity to insulin associated with type 2 diabetes. Consequently, the study of leptin is essential to understanding the relationship among appetite, energy balance and obesity.
Application
This Canine Leptin ELISA is used to measure & quantify Leptin levels in Metabolism & Endocrine & Neuroscience research.
This Is a 4-hour room temperature assay using 20 μL sample size
Research Category: Metabolism
Research Sub-Category: Obesity, Metabolic Disorders
This Is a 4-hour room temperature assay using 20 μL sample size
Research Category: Metabolism
Research Sub-Category: Obesity, Metabolic Disorders
Biochem/physiol Actions
Used to detect/quantify: Leptin
Packaging
96-well strip plate
Other Notes
Contact Technical Support.
Disclaimer
For research use only. Not for use in diagnostic procedures.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - ED ENV 1 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
Storage Class
10 - Combustible liquids
wgk
WGK 3
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