G2128
L-Glutamic acid hydrochloride
≥99% (HPLC), kainate, NMDA, and quisqualate agonist
Sinónimos:
(S)-2-Aminoglutaric acid, (S)-2-Aminopentanedioic acid ammonium salt, Glu HCl
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Fórmula empírica (notación de Hill):
C5H9NO4 · HCl
Número CAS:
Peso molecular:
183.59
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
205-315-9
MDL number:
Beilstein/REAXYS Number:
3565569
Servicio técnico
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Permítanos ayudarleNombre del producto
L-Glutamic acid hydrochloride, ≥99% (HPLC)
Quality Segment
assay
≥99% (HPLC)
SMILES string
Cl.N[C@@H](CCC(O)=O)C(O)=O
InChI
1S/C5H9NO4.ClH/c6-3(5(9)10)1-2-4(7)8;/h3H,1-2,6H2,(H,7,8)(H,9,10);1H/t3-;/m0./s1
InChI key
RPAJSBKBKSSMLJ-DFWYDOINSA-N
Gene Information
human ... GRIK1(2897), GRIK2(2898), GRIK3(2899), GRIK4(2900), GRIK5(2901)
General description
L-glutamate is the major excitatory neurotransmitter in mammalian central nervous system (CNS). It interacts with membrane bound glutamate receptors.
Application
L-Glutamic acid hydrochloride has been used as a nutrient additive to study the effect of increased dissolved inorganic nitrogen (DIN) on the uptake of dissolved organic nitrogen (DON) and dissolved organic carbon (DOC), in a nitrogen-limited headwater forest stream.
Biochem/physiol Actions
Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.
L-glutamate plays key roles in development, learning, memory, plasticity and cognition. It plays crucial role in the pathogenesis of neuropathological diseases such as epilepsy, schizophrenia, stroke, ischemia, ALS (amyotrophic lateral sclerosis), Huntington′s disease and Parkinson′s disease. Glutamate is also responsible for the activation of long-term potentiation (LTP) and long-term depression (LTD). Induction of glutamate receptors plays a key role in the pathophysiology of migraine.
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1
Clase de almacenamiento
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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