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504904 Ifenprodil Hemitartrate - CAS 23210-58-4 - Calbiochem

Ifenprodil Hemitartrate - CAS 23210-58-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: erythro-4-(2-(4-Benzylpiperidin-1-yl)-1-hydroxypropyl)phenol hemitartrate

Primary Target: GluN1/N2B subtype NMDA receptors
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
23210-58-4C₂₁H₂₇NO₂•0.5C₄H₆O₆
Description
Overview

This product has been discontinued.



A partial non-competitive antagonist highly selective for GluN1/N2B subtype NMDA receptors (IC50 = 0.15 µM, maximal inhibition ˜90%) over other subtypes (IC50 = 39, 29, 76 µM for GluN1/N2A, GluN1/N2C and GluN1/N2D subtype receptors, respectively). Frequently used in studies of various brain functions and disorders involving neural transmissions mediated by GluN1/N2B subtype NMDA receptors.

Please note that the molecular weight for this compound is batch-specific due to variable water content.

Catalogue Number504904
Brand Family Calbiochem®
Synonymserythro-4-(2-(4-Benzylpiperidin-1-yl)-1-hydroxypropyl)phenol hemitartrate
References
ReferencesZhang, H., et al. 2013. Mol. Brain. 6, 13.
Kishimoto, A., et al. 2013. J. Clin. Psychopharmacol. 33, 143.
Bhat, J., et al. 2013. Mol. Pharmacol. 83, 9.
Amico-Ruvio, S., et al. 2012. 82, 1074, 81.
Bhattacharya, P., et al. 2012. Med. Hypotheses. 79, 516.
Product Information
CAS number23210-58-4
FormWhite solid
Hill FormulaC₂₁H₂₇NO₂•0.5C₄H₆O₆
Chemical formulaC₂₁H₂₇NO₂•0.5C₄H₆O₆
Structure formula ImageStructure formula Image
Quality SegmentMQ100
Applications
Biological Information
Primary TargetGluN1/N2B subtype NMDA receptors
Primary Target IC<sub>50</sub>0.15 →M
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade ITEM Number
Catalogue Number GTIN
504904 0

Documentation

Ifenprodil Hemitartrate - CAS 23210-58-4 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Zhang, H., et al. 2013. Mol. Brain. 6, 13.
Kishimoto, A., et al. 2013. J. Clin. Psychopharmacol. 33, 143.
Bhat, J., et al. 2013. Mol. Pharmacol. 83, 9.
Amico-Ruvio, S., et al. 2012. 82, 1074, 81.
Bhattacharya, P., et al. 2012. Med. Hypotheses. 79, 516.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision17-July-2013 JSW
Synonymserythro-4-(2-(4-Benzylpiperidin-1-yl)-1-hydroxypropyl)phenol hemitartrate
DescriptionA partial non-competitive antagonist highly selective for GluN1/N2B subtype NMDA receptors (IC50 = 0.15 µM, maximal inhibition ˜90%) over other subtypes (IC50 = 39, 29, 76 µM for GluN1/N2A, GluN1/N2C and GluN1/N2D subtype receptors, respectively). Frequently used in studies of various brain functions and disorders involving neural transmissions mediated by GluN1/N2B subtype NMDA receptors.
FormWhite solid
CAS number23210-58-4
Chemical formulaC₂₁H₂₇NO₂•0.5C₄H₆O₆
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityDMSO (100 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesZhang, H., et al. 2013. Mol. Brain. 6, 13.
Kishimoto, A., et al. 2013. J. Clin. Psychopharmacol. 33, 143.
Bhat, J., et al. 2013. Mol. Pharmacol. 83, 9.
Amico-Ruvio, S., et al. 2012. 82, 1074, 81.
Bhattacharya, P., et al. 2012. Med. Hypotheses. 79, 516.