Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
-MAPmates™ that require a different assay buffer
-Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
-PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701)
-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
-GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
.
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Select A Species, Panel Type, Kit or Sample Type
To begin designing your MILLIPLEX® MAP kit select a species, a panel type or kit of interest.
Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
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96-Well Plate
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Add Additional Reagents (Buffer and Detection Kit is required for use with MAPmates)
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48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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Histone modifications regulate DNA transcription, repair, recombination, and replication, and can alter local chromatin architecture. Understanding histone modifications is key to uncovering epigenetic mechanisms of gene regulation. Merck grasps the complexity of this research and provides a growing line of kits, antibodies, and assays for studying histones and their modifications. Merck offers over 600 validated antibodies, recombinant proteins, and kits to analyze histone and histone-variant phosphorylation, methylation, acetylation, ubiquitination, and citrullination-the most widely studied histone modifications in epigenetics today.
Support every step of your genomic analysis workflow with the groundbreaking SmartFlare™ technology for live cell RNA detection and the molecular biology expertise of Novagen.
DNAmethylation is involved in the regulation of many cellular processes, including chromosome stability, chromatin structure, X chromosome inactivation, embryonic development, and transcription.
DNAmethylation is involved in the regulation of many cellular processes, including chromosome stability, chromatin structure, X chromosome inactivation, embryonic development, and transcription. DNAmethylation occurs mainly at the 5' position of cytosine bases and is mediated by enzymes called DNA methyltransferases (DNMT). Regions of methylated DNA can be bound by a variety of methylated DNA binding proteins (MBD).
Studying the mechanisms by which cells control changes in DNA structure and respond to DNA damage will help to elucidate the factors that cause aging, cellular degeneration, cancer, and death. Merck has the antibody solutions you need for your research.
Histone modifications regulate DNA transcription, repair, recombination, and replication, and can alter local chromatin architecture. The most commonly studied histone modifications are acetylation, phosphorylation, methylation, and ubiquitination.
Epigenetics describes heritable changes in gene expression caused by non-genetic mechanisms instead of by alterations in DNA sequence. Researchers can count on high quality reagents and expert support for their studies of gene regulation.
Cell health small molecule inhibitors are essential in the analysis of apoptosis, cell cycle regulation and other areas of focus related to cell viability.
Epigenetics describes heritable changes to chromatin that can influence gene function. As the basic mechanisms of these changes has become better understood, the influence of epigenetic regulation in development and disease has become a focus.
We offer an advanced line of CpG islands kits, antibodies, and reagents that simplifies assays and allows for fast and effective enrichment of target DNA and further genome-wide analyses.