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  • Histones and Histone Modifications | Life Science Research | Merck

    Histone modifications regulate DNA transcription, repair, recombination, and replication, and can alter local chromatin architecture. Understanding histone modifications is key to uncovering epigenetic mechanisms of gene regulation. Merck grasps the complexity of this research and provides a growing line of kits, antibodies, and assays for studying histones and their modifications. Merck offers over 600 validated antibodies, recombinant proteins, and kits to analyze histone and histone-variant phosphorylation, methylation, acetylation, ubiquitination, and citrullination-the most widely studied histone modifications in epigenetics today.
  • Explore What's Next with Merck

    If you're involved with drug development or manufacturing, you're in a unique position. Every day, you are creating possibilities to improve human health. While others wonder what's to come, you are building it. For decades, our customers have counted on MilliporeSigma's commitment to quality, safety and reliability to help them pave the way to the science of tomorrow. Now you can leverage MilliporeSigma's technological innovations to shape the future of pharmaceutical processing.
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