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AB15067 Anti-EMX1 Antibody

AB15067
100 µg  
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      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB15067
      DescriptionAnti-EMX1 Antibody
      Alternate Names
      • Empty spiracles homolog 1
      • Empty spiracles-like protein 1
      • empty spiracles homeobox 1
      • empty spiracles homolog 1 (Drosophila)
      Background InformationEMX1 and EMX2 are human homologs to the Drosophila developmental genes empty spiracles, and are specifically expressed in the developing telencephalic cortex. During the process of proliferation, migration, differentiation, and maturation, it has been reported that, while EMX2 is expressed in the dorsal telencephalon and small diencephalic regions, EMX1 expression is exclusively confined to pyramidal neurons of the dorsal telencephalon and remains localized in most cells of the cerebral cortex. Since EMX1 is expressed in both proliferating and differentiating neurons in the developing embryonic brain, it has also been shown to be a reliable marker of the embryonic pyramidal cell lineages.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human fetal brain lysates.

      PresentationPurified rabbit polyclonal in buffer containing PBS with 0.09% sodium azide.
      Applications
      ApplicationAnti-EMX1 Antibody detects level of EMX1 & has been published & validated for use in WB.
      Key Applications
      • Western Blotting
      Application NotesWestern Blotting:
      Recommended working dilutions are 1:250 – 1: 500.
      Biological Information
      ImmunogenSynthetic human EMX1 peptide, a.a. 274-290
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody is generated from rabbits immunized with a KLH conjugated synthetic peptided selected from human EMX1.
      Species Reactivity
      • Human
      Species Reactivity NoteReacts with human. Comparison of sequence homology suggests that this antibody may also react with mouse, rat, canine, bovine, and equine; however, reactivity with other species has not been tested.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • EMX1
      Purification MethodPeptide affinity purified
      UniProt Number
      UniProt SummaryFUNCTION: Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
      SUBCELLULAR LOCATION: Nucleus (Probable).
      TISSUE SPECIFICITY: Cerebral cortex.
      SIMILARITY: Belongs to the EMX homeobox family.
      SIMILARITY: Contains 1 homeobox DNA-binding domain.
      Molecular Weight30 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by Western blot on human fetal brain lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade ITEM Number
      Número de referencia GTIN
      AB15067 04053252628191

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      Categorías

      Life Science Research > Antibodies and Assays > Primary Antibodies