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407314 Anti-Integrin β₃ (Ab-1) Mouse mAb (290.5C10)

407314
  
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Tabla espec. clave

Species ReactivityHostAntibody Type
HMMonoclonal Antibody
Description
Overview

This product has been discontinued.



Recognizes the β3 integrin subunit in αvβ3 and αllbβ3 integrin protein complexes.

Catalogue Number407314
Brand Family Calbiochem®
SynonymsAnti-CD61
References
ReferencesHynes, R.O. 1992. Cell. 69, 11.
Phillips, D.R., et al. 1991. Cell. 65, 359.
Albelda, S.M. and Buck, C.A. 1990. FASEB J. 4, 2868.
Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol. 3, 179.
Hynes, R.O. 1987. Cell. 45, 549.
Product Information
FormLiquid
FormulationUndiluted ascites.
PreservativeNone
Quality SegmentMQ100
Applications
Key Applications Enzyme-Linked Immunosorbent Assay
Flow Cytometry
Immunoblotting (Western Blotting)
Immunoprecipitation
Paraffin Sections
Application NotesELISA (see comments)
Flow Cytometry (1:50-1:100)
Immunoblotting (1:50-1:100)
Paraffin Sections (1:50-1:100)
Immunoprecipitation (1:50-1:100)
Application CommentsThis antibody has also been reported to work for ELISA. Variables associated with assay conditions will dictate the proper working dilution.
Biological Information
Immunogenβ₃ integrin from M21 melanoma cells
ImmunogenHuman
Clone290.5C10
HostMouse
IsotypeIgG₁
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade ITEM Number
Número de referencia GTIN
407314 0

Documentation

Anti-Integrin β₃ (Ab-1) Mouse mAb (290.5C10) Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Anti-Integrin β₃ (Ab-1) Mouse mAb (290.5C10) Certificados de análisis

CargoNúmero de lote
407314

Referencias bibliográficas

Visión general referencias
Hynes, R.O. 1992. Cell. 69, 11.
Phillips, D.R., et al. 1991. Cell. 65, 359.
Albelda, S.M. and Buck, C.A. 1990. FASEB J. 4, 2868.
Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol. 3, 179.
Hynes, R.O. 1987. Cell. 45, 549.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision06-August-2007 RFH
SynonymsAnti-CD61
ApplicationELISA (see comments)
Flow Cytometry (1:50-1:100)
Immunoblotting (1:50-1:100)
Paraffin Sections (1:50-1:100)
Immunoprecipitation (1:50-1:100)
DescriptionMouse monoclonal antibody supplied as undiluted ascites. Recognizes the β3 integrin subunit in αvβ3 and αllbβ3 integrin protein complexes.
BackgroundThe integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated α and β subunits. CD61 non-covalently associates with CD41 (αIlb integrin) and is expressed by megakaryocytes and platelets. The CD61/CD41 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.
HostMouse
Immunogen speciesHuman
Immunogenβ₃ integrin from M21 melanoma cells
Clone290.5C10
IsotypeIgG₁
Specieshuman
FormLiquid
FormulationUndiluted ascites.
PreservativeNone
CommentsThis antibody has also been reported to work for ELISA. Variables associated with assay conditions will dictate the proper working dilution.
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling
ReferencesHynes, R.O. 1992. Cell. 69, 11.
Phillips, D.R., et al. 1991. Cell. 65, 359.
Albelda, S.M. and Buck, C.A. 1990. FASEB J. 4, 2868.
Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol. 3, 179.
Hynes, R.O. 1987. Cell. 45, 549.