Millipore Sigma Vibrant Logo

16-111 Anti-MAP Kinase 1/2 (Erk1/2) Antibody, agarose

Detect MAP Kinase 1/2 (Erk1/2) using this Anti-MAP Kinase 1/2 (Erk1/2) Antibody, agarose validated for use in IP.

Anti-MAP Kinase 1/2 (Erk1/2) Antibody, agarose: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Signaling Research Sub-Category: MAP Kinases Gene Symbol: MAPK1, p40, PRKM2, MAPK2, PRKM1, p42-MAPK, p38, p41, ERK, ERK-2, ERT1, P42MAPK, p41mapk, ERK2 UniProt Number: P28482
16-111
50 µg  
Recuperando precio...
No pudo obtenerse el precio
La cantidad mínima tiene que ser múltiplo de
Maximum Quantity is
Al finalizar el pedido Más información
Ahorró ()
 
—
Solicitar precio
—
Disponibilidad a confirmar Disponibilidad a confirmar
En existencia 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Contact Customer Service

      Ofertas especiales

       

      Póngase en contacto con el Servicio de Atención al Cliente

      Descripción

      Replacement Information

      Ofertas especiales

      100% Performance Guaranteed

      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, ChIPMGel ImmobilizedPolyclonal Antibody
      Description
      Catalogue Number16-111
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-MAP Kinase 1/2 (Erk1/2) Antibody, agarose
      OverviewAnti-MAP Kinase/Erk 1/2 (06-182) covalently coupled to Protein A agarose by dimethyl-pimelimidate.
      References
      Product Information
      FormatGel Immobilized
      PresentationPBS, pH 7.4 containing 0.05% sodium azide
      Applications
      ApplicationDetect MAP Kinase 1/2 (Erk1/2) using this Anti-MAP Kinase 1/2 (Erk1/2) Antibody, agarose validated for use in IP.
      Key Applications
      • Immunoprecipitation
      Application NotesSuitable for immunoprecipitation and affinity purification.
      Biological Information
      HostMouse
      Species Reactivity
      • Human
      • Mouse
      • Chicken
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
      Gene Symbol
      • MAPK1
      • p40
      • PRKM2
      • MAPK2
      • PRKM1
      • p42-MAPK
      • p38
      • p41
      • ERK
      • ERK-2
      • ERT1
      • P42MAPK
      • p41mapk
      • ERK2
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P28482 # Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4).
      COFACTOR: Magnesium (By similarity).
      SIZE: 360 amino acids; 41390 Da
      SUBUNIT: Interacts with MORG1 (By similarity). Binds to HIV-1 Nef through its SH3 domain. This interaction inhibits its tyrosine- kinase activity. Interacts with HSF4.
      DOMAIN: SwissProt: P28482 The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
      PTM: Dually phosphorylated on Thr-185 and Tyr-187, which activates the enzyme.
      SIMILARITY: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. & Contains 1 protein kinase domain.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoprecipitating MAP Kinase/Erk 1/2 from a RIPA lysate of 3T3/A31 cells
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions1 year at 4°C
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade ITEM Number
      Número de referencia GTIN
      16-111 04053252322471

      Documentation

      Anti-MAP Kinase 1/2 (Erk1/2) Antibody, agarose Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Anti-MAP Kinase 1/2 (Erk1/2) Antibody, agarose Certificados de análisis

      CargoNúmero de lote
      Anti-Kv4.2 - DAM1518887 DAM1518887
      Anti-MAP Kinase 1/2 (Erk1/2), agarose - 14961 14961
      Anti-MAP Kinase 1/2 (Erk1/2), agarose - 17169 17169
      Anti-MAP Kinase 1/2 (Erk1/2), agarose - 17716 17716
      Anti-MAP Kinase 1/2 (Erk1/2), agarose - 19048 19048
      Anti-MAP Kinase 1/2 (Erk1/2), agarose - 20719 20719
      Anti-MAP Kinase 1/2 (Erk1/2), agarose - 21054 21054
      Anti-MAP Kinase 1/2 (Erk1/2), agarose - 21659 21659
      Anti-MAP Kinase 1/2 (Erk1/2), agarose - 22904 22904
      Anti-MAP Kinase 1/2 (Erk1/2), agarose - 27644 27644
      Show more

      Productos y aplicaciones relacionados

      Related Products

      Número de referencia Descripción  
      04-797 Anti-phospho-MAP Kinase 1/2 (Erk1/2)(Thr185/Tyr187) Antibody, clone AW39, rabbit monoclonal Precios y disponibilidad
      05-157 Anti-MAP Kinase 2/Erk2 Antibody, clone 1B3B9 Precios y disponibilidad
      06-333 Anti-MAP Kinase 2/Erk2 Antibody Precios y disponibilidad
      FCMAB100P Milli-Mark Anti-Phospho-Erk1/2 Antibody (Thr202/Tyr204, Thr185/Tyr187)-PE Precios y disponibilidad

      Familias de productos

      Erk (MAP) Kinase Antibodies

      Millipore’s Erk Antibodies demonstrate specificity against Erk kinases, p44 and p42 MAP kinases. See below for related products, including proteins & kits based on the expertise of Upstate & Chemicon.
      Más información >>

      MAPK Antibodies, Proteins, Inhibitors, & Assays

      Offering hundreds of premium quality antibodies, enzymes, activity assays, and small molecule inhibitors for MAPK signaling research
      Más información >>

      Categorías

      Life Science Research > Antibodies and Assays > Primary Antibodies