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MABC708 Anti-SND1, clone 2D7 Antibody

Anti-SND1, clone 2D7 Antibody detects level of SND1 & has been published & validated for use in SND1.

Anti-SND1, clone 2D7 Antibody: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Apoptosis & Cancer Research Sub-Category: Tumor Markers Gene Symbol: SND1, TDRD11 UniProt Number: Q7KZF4
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MABC708
100 µL  
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      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMABC708
      DescriptionAnti-SND1, clone 2D7 Antibody
      Alternate Names
      • Staphylococcal nuclease domain-containing protein 1
      • 100 kDa coactivator
      • EBNA2 coactivator p100
      • Tudor domain-containing protein 11
      • p100 co-activator
      • SND1
      Background InformationStaphylococcal nuclease domain-containing protein 1, also known as 100 kDa coactivator or EBNA2 coactivator p100 or Tudor domain-containing protein 11 or p100 co-activator, and encoded by the gene name SND1 or TDRD11, plays an important role in PIM1 regulation of MYB acitivity and acts as a transcriptional activatior of EBNA-2. SND1 also interacts with EAV, NSP1,GTF2E1 and GTF2E2, and forms a ternary complex with STAT6 and POLR2A. SND1 ic localized to the cytoplasm and in IL-4 stimulated cells SND1 co-localizes with STAT6 in the nucleus. SND1 plays an important role in the assembly of STAT6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between STAT6 and CBP.
      References
      Product Information
      FormatAscites
      PresentationMouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
      Quality SegmentMQ100
      Applications
      ApplicationAnti-SND1, clone 2D7 Antibody detects level of SND1 & has been published & validated for use in SND1.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenPurified recombinant fragment of human SND1 expressed in E. Coli
      Clone2D7
      HostMouse
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • SND1
      • TDRD11
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~102 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HeLa, Jurkat, HepG2, and SMMC-7721 cell lysates.

      Western Blotting Analysis: A 1:500-1:2,000 dilution of this antibody detected SND1 in HeLa, Jurkat, HepG2, and SMMC-7721 cell lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade ITEM Number
      Número de referencia GTIN
      MABC708 04053252955426

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      Categorías

      Life Science Research > Antibodies and Assays > Primary Antibodies