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504904 Ifenprodil Hemitartrate - CAS 23210-58-4 - Calbiochem

Ifenprodil Hemitartrate - CAS 23210-58-4 - Calbiochem: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: erythro-4-(2-(4-Benzylpiperidin-1-yl)-1-hydroxypropyl)phenol hemitartrate

Primary Target: GluN1/N2B subtype NMDA receptors
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      Descripción

      Replacement Information

      Tabla espec. clave

      CAS #Empirical Formula
      23210-58-4C₂₁H₂₇NO₂•0.5C₄H₆O₆
      Description
      Overview

      This product has been discontinued.



      A partial non-competitive antagonist highly selective for GluN1/N2B subtype NMDA receptors (IC50 = 0.15 µM, maximal inhibition ˜90%) over other subtypes (IC50 = 39, 29, 76 µM for GluN1/N2A, GluN1/N2C and GluN1/N2D subtype receptors, respectively). Frequently used in studies of various brain functions and disorders involving neural transmissions mediated by GluN1/N2B subtype NMDA receptors.

      Please note that the molecular weight for this compound is batch-specific due to variable water content.

      Catalogue Number504904
      Brand Family Calbiochem®
      Synonymserythro-4-(2-(4-Benzylpiperidin-1-yl)-1-hydroxypropyl)phenol hemitartrate
      References
      ReferencesZhang, H., et al. 2013. Mol. Brain. 6, 13.
      Kishimoto, A., et al. 2013. J. Clin. Psychopharmacol. 33, 143.
      Bhat, J., et al. 2013. Mol. Pharmacol. 83, 9.
      Amico-Ruvio, S., et al. 2012. 82, 1074, 81.
      Bhattacharya, P., et al. 2012. Med. Hypotheses. 79, 516.
      Product Information
      CAS number23210-58-4
      FormWhite solid
      Hill FormulaC₂₁H₂₇NO₂•0.5C₄H₆O₆
      Chemical formulaC₂₁H₂₇NO₂•0.5C₄H₆O₆
      Structure formula ImageStructure formula Image
      Quality SegmentMQ100
      Applications
      Biological Information
      Primary TargetGluN1/N2B subtype NMDA receptors
      Primary Target IC<sub>50</sub>0.15 →M
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade ITEM Number
      Número de referencia GTIN
      504904 0

      Documentation

      Ifenprodil Hemitartrate - CAS 23210-58-4 - Calbiochem Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Referencias bibliográficas

      Visión general referencias
      Zhang, H., et al. 2013. Mol. Brain. 6, 13.
      Kishimoto, A., et al. 2013. J. Clin. Psychopharmacol. 33, 143.
      Bhat, J., et al. 2013. Mol. Pharmacol. 83, 9.
      Amico-Ruvio, S., et al. 2012. 82, 1074, 81.
      Bhattacharya, P., et al. 2012. Med. Hypotheses. 79, 516.
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision17-July-2013 JSW
      Synonymserythro-4-(2-(4-Benzylpiperidin-1-yl)-1-hydroxypropyl)phenol hemitartrate
      DescriptionA partial non-competitive antagonist highly selective for GluN1/N2B subtype NMDA receptors (IC50 = 0.15 µM, maximal inhibition ˜90%) over other subtypes (IC50 = 39, 29, 76 µM for GluN1/N2A, GluN1/N2C and GluN1/N2D subtype receptors, respectively). Frequently used in studies of various brain functions and disorders involving neural transmissions mediated by GluN1/N2B subtype NMDA receptors.
      FormWhite solid
      CAS number23210-58-4
      Chemical formulaC₂₁H₂₇NO₂•0.5C₄H₆O₆
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityDMSO (100 mM)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesZhang, H., et al. 2013. Mol. Brain. 6, 13.
      Kishimoto, A., et al. 2013. J. Clin. Psychopharmacol. 33, 143.
      Bhat, J., et al. 2013. Mol. Pharmacol. 83, 9.
      Amico-Ruvio, S., et al. 2012. 82, 1074, 81.
      Bhattacharya, P., et al. 2012. Med. Hypotheses. 79, 516.