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AB10320 Anti-Cytochrome P450 1B1 Antibody

Anti-1B1 Antibody detects level of 1B1 & has been published & validated for use in WB.

Anti-Cytochrome P450 1B1 Antibody : FDS (Fiches de données de sécurité), certificats d’analyse (CoA) et de qualité (CoQ), dossiers, brochures et autres documents disponibles.
Research Category: Metabolism Research Sub-Category: Enzymes & Biochemistry Gene Symbol: CP1B, CYPIB1 , EC 1.14.14.1 , GLC3A UniProt Number: Q16678
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AB10320
50 µL  
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      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBRbSerumPolyclonal Antibody
      Description
      Catalogue NumberAB10320
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Cytochrome P450 1B1 Antibody
      Alternate Names
      • Cytochrome P450 1B1
      Background InformationCytochrome P450 1B1 (CYP1B1) is active in the metabolism of estrogens to reactive catechols and of different procarcinogens. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids.
      References
      Product Information
      FormatSerum
      PresentationRaw rabbit serum with 0.05% sodium azide.
      Quality SegmentMQ100
      Applications
      ApplicationAnti-1B1 Antibody detects level of 1B1 & has been published & validated for use in WB.
      Key Applications
      • Western Blotting
      Application NotesSuggested dilutions:
      Western Blot: 1:5000
      Biological Information
      ImmunogenRecombinant human 1B1
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.
      Gene Symbol
      • CP1B
      • CYPIB1
      • EC 1.14.14.1
      • GLC3A
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q16678 # Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
      SIZE: 543 amino acids; 60846 Da
      SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
      SIMILARITY: SwissProt:Q16678 # Belongs to the cytochrome P450 family.
      Molecular Weight61kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by immunoblot.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C for up to 12 months from date of receipt.
      Packaging Information
      Material Size50 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade ITEM Number
      Référence GTIN
      AB10320 04053252583070