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09-836 Anti-phospho-Histone H1.B (Ser27) Antibody

09-836
100 ug  
Purchase on Sigma-Aldrich

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Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, MplexRbPurifiedPolyclonal Antibody
Description
Catalogue Number09-836
DescriptionAnti-phospho-Histone H1.B (Ser27) Antibody
Background InformationHistones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into 30nm chromatin fibers and higher order structures.
References
Product Information
FormatPurified
Control
  • Untreated and colcemid-treated HeLa acid extract.
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl, and 0.05% sodium azide.
Applications
ApplicationAnti-phospho-Histone H1.B (Ser27) Antibody is a high quality Rabbit Polyclonal Antibody for the detection of phospho-Histone H1.B (Ser27) & has been validated in WB, Mplex.
Key Applications
  • Western Blotting
  • Multiplexing
Biological Information
ImmunogenKLH-conjugated synthetic linear peptide corresponding to the region at and around phosphorylated serine 27 of histone H1.B.
EpitopePhosphorylated H1.B (Ser27)
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes phosphorylated serine 27 at and around the N-terminal region of histone H1.B.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Modifications
  • Phosphorylation
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight35 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by western blot on untreated and colcemid-treated HeLa acid extract.

Western Blotting Analysis: 0.1 µg/mL of this antibody detected phospho-Histone H1.B (Ser27) in untreated and colcemid-treated HeLa acid extract.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8ºC from date of receipt.
Packaging Information
Material Size100 ug
Transport Information
Supplemental Information
Specifications
Global Trade ITEM Number
Référence GTIN
09-836 04053252335839

Produits & Applications associés

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Référence Description
06-597 Anti-phospho-Histone H1 Antibody

Familles de produits

Catégories

Life Science Research > Antibodies and Assays > Primary Antibodies