670359
Acetylthiomethyl-diphenylphosphine borane complex
≥98.0%
Synonym(s):
(T-4)-[S-[(Diphenylphosphino-κP)methyl] ethanethioate]trihydroboron
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About This Item
assay
≥98.0%
form
solid
reaction suitability
reaction type: click chemistry, reagent type: ligand
reaction type: Staudinger Reaction
mp
52-55 °C
functional group
phosphine
storage temp.
2-8°C
SMILES string
B.CC(=O)SCP(c1ccccc1)c2ccccc2
InChI
1S/C15H15OPS.BH3/c1-13(16)18-12-17(14-8-4-2-5-9-14)15-10-6-3-7-11-15;/h2-11H,12H2,1H3;1H3
InChI key
MXPNVFCCEGQGEN-UHFFFAOYSA-N
Application
- Traceless Staudinger ligation reagent with borane protecting group.
- The borane group stabilizes the phosphine against oxidation and can be easily removed with mild basic or acidic conditions to yield the active phosphine.
- After reaction with an azide, the phosphine is eliminated in the presence of water to yield a native amide bond.
- Used in the synthesis of cyclic peptides.
Packaging
Legal Information
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Listings
Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.
670359-250MG: + 670359-BULK: + 670359-1G: + 670359-VAR:
jan
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