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Merck

62840

L-Lysine

≥98.0% (NT), for peptide synthesis

Synonym(s):

(S)-2,6-Diaminocaproic acid

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About This Item

Linear Formula:
H2N(CH2)4CH(NH2)CO2H
CAS Number:
56-87-1
Molecular Weight:
146.19
NACRES:
NA.22
PubChem Substance ID:
57651911
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-294-2
MDL number:
MFCD00064433
Beilstein/REAXYS Number:
1722531

Key Documents

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Product Name

L-Lysine, crystallized, ≥98.0% (NT)

SMILES string

NCCCC[C@H](N)C(O)=O

InChI key

KDXKERNSBIXSRK-YFKPBYRVSA-N

InChI

1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/t5-/m0/s1

assay

≥98.0% (NT)

form

solid

optical activity

[α]20/D +26.0±1.0°, c = 2% in 6 M HCl

quality

crystallized

reaction suitability

reaction type: solution phase peptide synthesis

impurities

≤1% water

mp

215 °C (dec.) (lit.)
~215 °C (dec.)

solubility

H2O: 0.1 g/mL, clear, colorless to very faintly greenish-yellow

application(s)

peptide synthesis

Quality Level

300

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Application

L-lysine serves as a precursor in the formation of polymeric structures.It is also used for the synthesis and modification of chitosan resin.

General description

L-lysine is an amino acid commonly used as a building block in solid-phase peptide synthesis (SSPS).

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG8175
BCCG0341
BCCF1401
BCCD5443
BCCC8157

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Hierarchical nanofabrication of microporous crystals with ordered mesoporosity.
Fan W
Nature Materials, 7(12), 984-984 (2008)
Sofia Faraasen et al.
Pharmaceutical research, 20(2), 237-246 (2003-03-15)
The purpose of this study was to demonstrate specific receptor-mediated targeting of phagocytes by functional surface coatings of microparticles, shielding from nonspecific phagocytosis and allowing ligand-specific interactions via molecular recognition. Coatings of the comb polymer poly(L-lysine)-g-poly(ethylene glycol) (PLL-g-PEG) were investigated
Valentina R Minciacchi et al.
Oncotarget, 6(13), 11327-11341 (2015-04-11)
Large oncosomes (LO) are atypically large (1-10 µm diameter) cancer-derived extracellular vesicles (EVs), originating from the shedding of membrane blebs and associated with advanced disease. We report that 25% of the proteins, identified by a quantitative proteomics analysis, are differentially
Lubin Jiang et al.
Nature, 499(7457), 223-227 (2013-07-05)
The variant antigen Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), which is expressed on the surface of P. falciparum-infected red blood cells, is a critical virulence factor for malaria. Each parasite has 60 antigenically distinct var genes that each code
Amélie Fradet-Turcotte et al.
Nature, 499(7456), 50-54 (2013-06-14)
53BP1 (also called TP53BP1) is a chromatin-associated factor that promotes immunoglobulin class switching and DNA double-strand-break (DSB) repair by non-homologous end joining. To accomplish its function in DNA repair, 53BP1 accumulates at DSB sites downstream of the RNF168 ubiquitin ligase.
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