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Merck

860512P

Avanti

C12 Ceramide (d18:1/12:0)

Avanti Research - A Croda Brand

Synonym(s):

N-lauroyl-D-erythro-sphingosine

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About This Item

Empirical Formula (Hill Notation):
C30H59NO3
CAS Number:
Molecular Weight:
481.79
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (860512P-10mg), pkg of 1 × 25 mg (860512P-25mg), pkg of 1 × 5 mg (860512P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C30H59NO3/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-29(33)28(27-32)31-30(34)26-24-22-20-17-12-10-8-6-4-2/h23,25,28-29,32-33H,3-22,24,26-27H2,1-2H3,(H,31,34)/b25-23+/t28-,29+/m0/s1

InChI key

HXFPPRPLRSPNIB-VARSQMIESA-N

General description

C12 Ceramide (d18:1/12:0) is a synthetic ceramide containing sphingosine with lauric acid.

Application

C12 Ceramide (d18:1/12:0) or N-lauroyl-D-erythro-sphingosine has been used:
  • as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions
  • as an internal standard for lipid extraction in U87MG (human glioma cell line)
  • as an internal standard for the quantification of ceramide using liquid chromatography-mass spectrometry (LC-MS) in rat tissues

Biochem/physiol Actions

Ceramides are signaling sphingolipids, which are implicated in regulating stress responses and inflammation. It also regulates cell growth arrest, differentiation and apoptosis.

Packaging

5 mL Amber Glass Screw Cap Vial (860512P-10mg)
5 mL Amber Glass Screw Cap Vial (860512P-25mg)
5 mL Amber Glass Screw Cap Vial (860512P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


Storage Class

11 - Combustible Solids

wgk

WGK 3



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