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860624P

Avanti

C18:1 Dihydroceramide (d18:0/18:1(9Z))

Avanti Research™ - A Croda Brand

Synonym(s):

N-oleoyl-D-erythro-sphinganine

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About This Item

Empirical Formula (Hill Notation):
C36H71NO3
CAS Number:
34227-83-3
Molecular Weight:
565.95
MDL number:
MFCD22495332
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

C18:1 Dihydroceramide (d18:0/18:1(9Z)), Avanti Research™ - A Croda Brand 860624P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (860624P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860624P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCC/C=C\CCCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC

InChI

1S/C36H71NO3/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-36(40)37-34(33-38)35(39)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,34-35,38-39H,3-16,19-33H2,1-2H3,(H,37,40)/b18-17-/t34-,35+/m0/s1

InChI key

MJQIARGPQMNBGT-WWUCIAQXSA-N

General description

C18:1 Dihydroceramide (d18:0/18:1(9Z)) is a synthetic lipid. Dihydroceramide belongs to the ceramide family. It contains sphinganine, which is devoid of the 4,5-trans-double bond in the sphingoid base backbone.

Application

C18:1 Dihydroceramide (d18:0/18:1(9Z)) has been used as an internal standard to quantify the levels of serum and skeletal muscle lipids extracted from muscle tissue by liquid chromatography-mass spectrometry (MS) analysis. It has also been used as an standard to study its structural characterization by positive-ionization mode 193 nm ultraviolet photodissociation (UVPD)-mass spectrometry/MS.

Biochem/physiol Actions

Dihydroceramide is synthesized by the N-acylation of dihydrosphingosine. It functions as an inactive precursor for ceramide in de-novo sphingolipid synthesis. (Dihydro)-ceramide desaturase catalyzes the conversion of dihydroceramide to ceramide by the addition of C4–5 trans-double bond in the sphingoid backbone. Dihydroceramide has an ability to induce autophagy.

Packaging

5 mL Amber Glass Screw Cap Vial (860624P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

wgk

WGK 3

Storage Class

11 - Combustible Solids

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