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T-038

(+)-11-Nor-Δ9-THC-9-carboxylic acid glucuronide solution

100 μg/mL in methanol, ampule of 1 mL, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C27H36O10
CAS Number:
1362113-32-3
Molecular Weight:
520.57
NACRES:
NA.24
UNSPSC Code:
41116107
EC Number:
200-659-6
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grade

certified reference material

Quality Segment

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

cannabis testing
forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

CCCCCc1cc(O)c2C3C=C(CCC3C(C)(C)Oc2c1)C(=O)OC4OC(C(O)C(O)C4O)C(O)=O

InChI

1S/C27H36O10/c1-4-5-6-7-13-10-17(28)19-15-12-14(8-9-16(15)27(2,3)37-18(19)11-13)25(34)36-26-22(31)20(29)21(30)23(35-26)24(32)33/h10-12,15-16,20-23,26,28-31H,4-9H2,1-3H3,(H,32,33)

InChI key

UWXZAZRSQQLWKH-UHFFFAOYSA-N

General description

11-Nor-Δ9-THC-9-carboxylic acid glucuronide is the phase II metabolite of the phytocannabinoid ∆9-tetrahydrocannabinol (THC). This certified Snap-N-Spike® reference solution is suitable for numerous GC/MS or LC/MS applications from pharmaceutical testing and research to clinical toxicology or forensic analysis. This Certified Reference Material provides added value in allowing calibration of THC acid glucuronide by LC-MS/MS methods without the need for an added hydrolysis step.

Application

The Certified Spiking Solution® is suitable for (+)-11-Nor-Δ9-THC-9-carboxylic acid glucuronide testing by HPLC, GC/MS, or LC-MS/MS methods in forensic analysis, clinical toxicology, urine drug testing, and Cannabis potency or impurity profiling testing applications. The Certified Reference Material (CRM) in solution can also be used as follows:
  • Development of an automated sample preparation method based on solid phase extraction (SPE) to determine ∆9-tetrahydrocannabinol (THC) and its three primary metabolites in a variety of matrices, such as serum, saliva, and urine using liquid chromatography-mass spectrometry (LC-MS)
  • Liquid chromatographic-tandem mass spectrometric (LC-MS/MS) determination of cannabinoids and their metabolites in whole blood samples
  • Detection and quantification of 11-Nor-∆9-tetrahydrocannabinol-9-carboxylic acid glucuronide (THC-COOH-glu) in hair samples by ultra-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)
  • Simultaneous residue analysis of phytocannabinoids, their metabolites, and amphetamine-type stimulants (ATS) in 11 hair samples obtained from drug users by liquid chromatography-high resolution mass spectrometry (LC-HRMS)
  • Determination of measurement uncertainty in the quantitative analysis of 11-nor-∆9-tetrahydrocannabinol-9-carboxylic acid (THC-COOH) and its glucuronide analogue (THC-COOH-glu) from urine samples by using LC-MS/MS

Features and Benefits

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Other Notes

Not to be used for immunoassay

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Group 4: Flammable liquids + Alcohols + Hazardous rank II

fsl

T-038-1ML:4.548173317151E12

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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