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Merck

5.08739

Cycloheximide

InSolution, ≥98%

Synonym(s):

InSolution Cycloheximide, High Purity, 4-(( R)-2-((1 S,3 S,5 S)-3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)piperidine-2,6-dione, Actidione, 4-((R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)piperidine-2,6-dione, Actidione

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About This Item

Empirical Formula (Hill Notation):
C15H23NO4
CAS Number:
66-81-9
Molecular Weight:
281.35
UNSPSC Code:
12352005
MDL number:
MFCD00082346

Key Documents

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Product Name

Cycloheximide, InSolution, ≥98%

InChI

1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1

InChI key

YPHMISFOHDHNIV-FSZOTQKASA-N

assay

≥98% (HPLC)

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles
desiccated (hygroscopic)
protect from light

storage temp.

−20°C

Quality Level

200

Biochem/physiol Actions

Cell permeable: yes
Primary Target
translocase enzyme
Reversible: yes

Disclaimer

Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)

Other Notes

Christner, C., et al. 1999. J. Med. Chem.42, 3615.
Lu, Q., et al. 1996. Arch. Biochem. Biophys.334, 175.

Chow, S.C., et al. 1995. Exp. Cell Res.216, 149.
Cotter, T.G., et al. 1992. Anticancer Res.12, 773.
Takano, Y.S., et al. 1991. J. Pathol.163, 329.
Waring, P. 1990. J. Biol. Chem.265, 14476.

Physical form

A 300 mM (100 mg/1.185 ml) sterile-filtered solution of Cycloheximide, High Purity (Cat. No. 239764) in DMSO.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 3 - Muta. 2 - Repr. 1B

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Certificates of Analysis (COA)

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