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Merck

8.18710

Urea

for synthesis

Synonym(s):

Carbamide, Carbonyl diamide, Diaminomethanone, Carbonyldiamine, Carbamide, Carbonyldiamide

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About This Item

Linear Formula:
NH2CONH2
CAS Number:
57-13-6
Molecular Weight:
60.06
UNSPSC Code:
12352111
NACRES:
NA.22
EC Index Number:
200-315-5
MDL number:
MFCD00008022
Beilstein/REAXYS Number:
635724

Key Documents

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Product Name

Urea, for synthesis

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

vapor pressure

<0.1 hPa ( 20 °C)

potency

8471 mg/kg LD50, oral (Rat)
8200 mg/kg LD50, skin (Rat)

pH

9 (20 °C, 100 g/L in H2O)

mp

132-135 °C (lit.)

solubility

1000 g/L

density

1.335 g/mL at 25 °C (lit.)

bulk density

720‑760 kg/m3

storage temp.

2-30°C

Quality Level

200

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Analysis Note

Assay (ex N): ≥ 99.0 %
Melting range (lower value): ≥ 132 °C
Melting range (upper value): ≤ 135 °C
Identity (IR): passes test

Application

Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
8.18710.100004022536443355
8.18710.500004022536443362

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