Key Documents

View All Documentation

EDS

Ethylenediaminetetraacetic acid

Name: Ethylenediaminetetraacetic acid
Brand: SIAL

BioUltra, anhydrous, ≥99% (titration)

Synonym(s):

(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid

Select a Size

Change View

About This Item

Linear Formula:

(HO₂CCH₂)₂NCH₂CH₂N(CH₂CO₂H)₂

CAS Number:

60-00-4

Molecular Weight:

292.24

NACRES:

NA.77

PubChem Substance ID:

24894713

eCl@ss:

39030907

UNSPSC Code:

12352116

EC Number:

200-449-4

MDL number:

MFCD00003541

Beilstein/REAXYS Number:

1716295

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

grade

anhydrous

Quality Level

200

product line

BioUltra

assay

≥99% (titration)

form

powder

reaction suitability

reagent type: chelator

pH

2.5 (23 °C, 10 g/L)

mp

250 °C (dec.) (lit.)

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

Description

General description

Ethylenediaminetetraacetic acid (EDTA) is a substituted diamine and a versatile compound in household with industrial applications. EDTA chelates metal divalent cations like calcium, magnesium, zinc, copper, manganese by forming metal-EDTA complexes. It finds its application in cleaning products and detergent formulations. In paper and pulp industries, EDTA reduces the adverse effect of metal ions on bleaching. It functions as an antibacterial agent by removing calcium and magnesium divalent cations from the outer membrane and causes loss of lipopolysaccharide from the membrane, making the bacteria susceptible to bactericidal agents. Free EDTA has adverse effect on reproduction and development in mammals. EDTA can chelate ions from deposits that contribute to atherosclerosis, cancers and heart diseases. It can help to overcome cell membrane injury by reducing radical reactions and oxidation processes. It binds to calcium and reduces the risk of hypercalcinemia in cancer patients. Transmembrane ammonium EDTA gradient method aids in drug delivery, increasing drug retention and efficacy of therapeutics and lowers the cytotoxicity levels.

Application

EDTA has been used:

as a medium supplement in embryo culture using synthetic oviduct fluid culture 1 (SOFC1) medium
in incubation of EpCAM+ cells with fluorescein isothiocyanate (FITC) conjugated antibody for cell sorting analysis
in pre-treatment of single cell suspension of dendritic cells from spleen for cell sorting with magnetic beads

Still not finding the right product?

Explore all of our products under Ethylenediaminetetraacetic acid

signalword

Warning

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

target_organs

Respiratory Tract

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Irrit. 2 - STOT RE 2 Inhalation

wgk

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Class I Designated Chemical Substances

prtr

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

EDS-500G:4.548173387154E12 + EDS-100G:4.54817338713E12 + EDS-1KG:4.548173387147E12

jan

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

The application of EDTA in drug delivery systems: doxorubicin liposomes loaded via NH4EDTA gradient

Song Y, et al.

International journal of nanomedicine, 9, 3611-3621 (2014)

Effect of the absence or presence of various protein supplements on further development of bovine oocytes during in vitro maturation

Ali A and Sirard M

Biology of Reproduction, 66(4), 901-905 (2002)

Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity

Menges M, et al.

The Journal of Experimental Medicine, 195(1), 15-22 (2002)

View All Related Papers

Global Trade Item Number

SKU	GTIN
ZMQSPENVJ	04053252026973
EDSPAK00J	04053252021251
EDSPAK0A1	04054839323430
EDSPAK001	04053252468704
MAB1435	04053252610950