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Merck

P3440

Polyoxyethylene (40) stearate

Synonym(s):

Myrj 52

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About This Item

CAS Number:
9004-99-3
UNSPSC Code:
12161900
NACRES:
NA.25
MDL number:
MFCD00148007

Key Documents

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form

powder

SMILES string

O(CCO)C(=O)CCCCCCCCCCCCCCCCC

InChI

1S/C20H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)23-19-18-21/h21H,2-19H2,1H3

InChI key

RFVNOJDQRGSOEL-UHFFFAOYSA-N

description

non-ionic

application(s)

detection

Quality Level

200

Related Categories

General description

Polyoxyethylene (40) stearate is a neutral surfactant.

Application

Polyoxyethylene (40) stearate has been used in a study to assess the phase behaviors of special hot microemulsion to produce drug-loaded nanostructured lipid carriers. It has also been used in a study to investigate its effects on multidrug resistance (MDR).

Storage Class

11 - Combustible Solids

wgk

WGK 1

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

P3440-BULK: + P3440-250G: + P3440-VAR:

jan

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Certificates of Analysis (COA)

Lot/Batch Number
MKBX3528V
MKBV6365V
MKBV0889V
MKBT6708V
MKBT3185V

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Lingying Luo et al.
The AAPS journal, 9(3), E329-E335 (2008-01-04)
Multidrug resistance (MDR) is one of the major obstacles limiting the efficacy of cancer chemotherapy. Identification of new and effective MDR reversal agents is needed. In this study, the effects of polyoxyethylene 40 stearate (PS40) on MDR were evaluated via
Michalakis Savva et al.
Colloids and surfaces. A, Physicochemical and engineering aspects, 325(1-2), 1-6 (2009-07-18)
The feasibility of a method based on mass preservation [G. Schwarz, J. Zhang, Chem. Phys. Lipids, 110 (2001) 35-45] to determine the solubility of Cholesterol in water from monomolecular films on air/water interface was investigated. Using a mass balance equation
Effects of polyoxyethylene (40) stearate on the activity of P-glycoprotein and cytochrome P450.
Zhu, S., et al.
European Journal of Pharmaceutical Sciences, 37, 8-8 (2009)
Klaus Raith et al.
International journal of pharmaceutics, 319(1-2), 1-12 (2006-05-30)
The in-depth characterization of excipients is a prerequisite for their safe application in pharmaceutical products. In case of surfactants, this task can be a challenge, since many industrial products are mixtures of variable composition. In this work, mass spectrometric methods
Hong Yuan et al.
Colloids and surfaces. B, Biointerfaces, 60(2), 174-179 (2007-07-28)
Nanostructured lipid carriers (NLC) made from mixtures of solid and spatially incompatible liquid lipids were prepared by melt-emulsification. Their drug loading capacity and releasing properties of progesterone were compared with those of solid lipid nanoparticles (SLN), and the NLC prepared
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