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この商品について
実験式（ヒル表記法）:
C39H76O8PNa
CAS番号:
分子量:
726.98
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
description
1,2-distearoyl-sn-glycero-3-phosphate (sodium salt)
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (830865P-25mg), pkg of 1 × 500 mg (830865P-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCC)O
InChI
1S/C39H77O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(40)45-35-37(36-46-48(42,43)44)47-39(41)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h37H,3-36H2,1-2H3,(H2,42,43,44);/q;+1/p-1/t37-;/m1./s1
InChI key
ALPWRKFXEOAUDR-GKEJWYBXSA-M
General description
Phosphatidic acid (PA) has two fatty acids and one phosphate group attached to a glycerol backbone. The two fatty acids are present at position sn-1 and sn-2 of the C-atoms and the phosphate group is present in the sn-3 position of the C-atom.
Application
18:0 PA may be used:
- as a component in the bilayer to study its vesiculation ability on different coat protein I (COPI) fission factor
- to study its effects on intracellular Ca2+ concentration ([Ca2+]i) in C6 rat glioma and L2071 mouse fibroblast cells
- to study its effects on phosphorylation of cytochrome b(558) alpha chain (p22phox)
Biochem/physiol Actions
Phosphatidic acid (PA) acts as a biosynthetic precursor for the production of membrane glycerophospholipid and triacylglycerol. It participates in the modulation of mammalian target of rapamycin (mTOR) pathway. It may also participate in membrane trafficking, specifically in membrane fusion and fission.
Packaging
20 mL Clear Glass Screw Cap Vial (830865P-500mg)
5 mL Amber Glass Screw Cap Vial (830865P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
保管分類
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable