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Merck

1.06007

Supelco

メタノール

≥99.9% (GC), gradient grade, suitable for HPLC, LiChrosolv®, reag. Ph. Eur.

別名:

メチルアルコール

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この商品について

化学式:
CH3OH
CAS番号:
分子量:
32.04
Beilstein:
1098229
MDL番号:
UNSPSCコード:
12191502
EC Index Number:
200-659-6
NACRES:
NA.03
Bp:
64.7 °C (lit.)
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製品名

メタノール, gradient grade for liquid chromatography LiChrosolv® Reag. Ph Eur

グレード

gradient grade
gradient grade

品質水準

認証

reag. Ph. Eur.

蒸気密度

1.11 (vs air)

蒸気圧

128 hPa ( 20 °C)
410 mmHg ( 50 °C)
97.68 mmHg ( 20 °C)

製品種目

LiChrosolv®

アッセイ

≥99.9% (GC)

フォーム

liquid

自己発火温度

725 °F

有効性

5628 mg/kg LD50, oral (Rat)
17100 mg/kg LD50, skin (Rabbit)

expl. lim.

36 %

テクニック

HPLC: suitable

不純物

≤0.0002 meq/g Acidity
≤0.0002 meq/g Alkalinity
≤0.02% Water

蒸発残留物質

≤2.0 mg/L

APHA: ≤10

透過率

210 nm, ≥20%
220 nm, ≥60%
230 nm, ≥75%
235 nm, ≥83%
250 nm, ≥95%
260 nm, ≥98%

屈折率

n20/D 1.329 (lit.)

動粘度

0.54-0.59 cSt(20 °C)

bp

64.7 °C (lit.)

mp

−98 °C (lit.)

転移温度

flash point 9.7 °C

密度

0.791 g/mL at 25 °C (lit.)

UV吸収

λ: 225 nm Amax: ≤0.170

フォーマット

neat

保管温度

2-30°C

SMILES記法

CO

InChI

1S/CH4O/c1-2/h2H,1H3

InChI Key

OKKJLVBELUTLKV-UHFFFAOYSA-N

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詳細

LiChrosolv® solvents were specially formulated to meet the demanding needs of analytical HPLC applications. With exceptional UV transmittance, minimal particle count, and controlled acidity and alkalinity, our solvents ensure reproducible separations every time. The low evaporation residue level further enhances their performance, making them the ideal choice for high-quality results. The product line includes both "gradient grade" and "isocratic grade" solvents, specifically designed to reduce the gradient effect during separations. This tailored approach allows for optimal consistency and accuracy in your analytical processes, helping you achieve the best possible outcomes in your chromatography work.

Now Available with Data Matrix Code

This high-quality HPLC-grade solvent now features a unique Data Matrix Code on its label, providing digital access to essential product information such as batch number, product number, and expiry date. Unlike standard barcodes, our DMCs feature a unique serial number for each bottle, enabling you to monitor and trace every bottle individually. With standard barcodes, all bottles from the same batch look identical. Our solution gives you true bottle-level traceability for greater control and compliance in the lab.
Know more about our data matrix code-labeled HPLC-grade solvents.

アプリケーション

  • Mobile Phase in HPLC: Widely utilized as a polarsolvent in both reversed-phase and normal-phase HPLC, suitable for varioustypes of analytes.
  • Gradient Elution: Ideal for gradient elutiontechniques, enhancing the resolution and separation efficiency of complexmixtures.
  • Pharmaceutical Quality Control: Used in the qualitycontrol of pharmaceutical products to analyze formulations, stability, anddegradation products.
  • Food and Beverage Analysis: Employed in HPLC for theanalysis of additives, preservatives, and flavor compounds in food and beveragesamples.
  • Natural Product Analysis: Utilized in the separationand characterization of natural products, such as alkaloids and flavonoids,from plant extracts.

特徴および利点

  • High Purity: Formulated with minimal impurities,ensuring reliable and reproducible results essential for sensitive analyticalapplications.
  • Excellent UV Transparency: Provides optimal UVtransmittance, facilitating accurate detection and enhancing sensitivity inHPLC analyses.
  • Low Evaporation Residue: Minimizes contaminationrisk, leading to cleaner separations and improved analytical reliability.
  • Batch-to-Batch Consistency: Ensures uniform qualityand performance across different production batches, enhancing reproducibilityand confidence in analytical results.

調製ノート

Microfilteredby 0.2 μm filter

アナリシスノート

Evaporation Number: 1.9
Purity (GC): ≥ 99.9 %
Identity (IR): conforms
Evaporation residue: ≤ 2.0 mg/l
Water: ≤ 0.02 %
Color: ≤ 10 Hazen
Density (d 20 °C/20 °C): 0.791 - 0.793
Boiling point: 64 - 65 °C
Acidity: ≤ 0.0002 meq/g
Alkalinity: ≤ 0.0002 meq/g
Gradient grade (at 235 nm): ≤ 2.0 mAU
Gradient grade (at 254 nm): ≤ 1.0 mAU
Fluorescence (as quinine at 254 nm): ≤ 1.0 ppb
Fluorescence (as quinine at 365 nm): ≤ 0.5 ppb
Transmission (at 210 nm): ≥ 20 %
Transmission (at 220 nm): ≥ 60 %
Transmission (at 230 nm): ≥ 75 %
Transmission (at 235 nm): ≥ 83 %
Transmission (at 250 nm): ≥ 95 %
Transmission (from 260 nm): ≥ 98 %
Absorbance (at 225 nm): ≤ 0.170
Filtered by 0.2 µm filter.
Suitable for UPLC / UHPLC /Ultra HPLC - instruments.
Conforms to Methanol R1 and R2 according to Reag. Ph Eur;
conforms to the requirements of ACS for liquid chromatography suitability.

その他情報

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

法的情報

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

ピクトグラム

FlameSkull and crossbonesHealth hazard

シグナルワード

Danger

危険有害性情報

危険有害性の分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

ターゲットの組織

Eyes,Central nervous system

保管分類コード

3 - Flammable liquids

WGK

WGK 2

引火点(°F)

49.5 °F - closed cup

引火点(℃)

9.7 °C - closed cup


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

消防法

第4類:引火性液体
アルコール類
危険等級II

労働安全衛生法名称等を表示すべき危険物及び有害物

名称等を表示すべき危険物及び有害物

労働安全衛生法名称等を通知すべき危険物及び有害物

名称等を通知すべき危険物及び有害物

Jan Code

1060079912:
1060075000:
1060079913:
1060072500:4548174003756
NAPE1060074000:
AR11060074000:
1060079183:
1060079185:
5930812505:
1060074008:
1060070000:
1060079910:
1060079010:
1060071000:
1060071024:
1060079914:
CO1C1060074000:
1060074004:
1060079030:
1060072524:
1060075005:
TH11060074004:
1060075024:
1060078888:
1060074000:
1060072508:
1060071045:
CL11060074004/1:



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プロトコル

Sildenafil Citrate Method (HPLC) following USP Monograph on Ascentis Express C18 with UV detection

Aripiprazole is an atypical antipsychotic and a partial dopamine agonist. It is primarily used in the treatment of schizophrenia, bipolar disorder, major depressive disorder, tic disorders, and irritability associated with autism. Aripiprazole was first approved by the U.S. Food and DrugAdministration in November 2002 for schizophrenia and by the European Medicines Agency in June 2004 for acute manic and mixed episodes associated with bipolar disorder.

Powdered black pepper was chosen as example for dietary supplements, being a source for pierine. It is tested according to the current United States Pharmacopeia (USP) guidelines using HPTLC and HPLC.

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資料

Apixaban is sold under the tradename Eliquis and at present no pharmacopeial monographs are available for Axpixaban using either an assay and/or organic impurity profiling method. A newly developed and validated HPLC-UV method using a column with C18 solid core particles is demonstrated.

TLC plates, with silica gel, gypsum as binder, International Pharmacopoeia compliant, for identification of Atenolol and Chlorthalidone in tablets

TLC plates, with silica gel, gypsum as binder, International Pharmacopoeia compliant, for identification of Atenolol and Chlorthalidone in tablets

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グローバルトレードアイテム番号

カタログ番号GTIN
1.06007.100004022536071060
1.06007.250004022536071084
1.06007.400004022536658285