カラゾロール

Name: カラゾロール
Brand: SIAL

analytical standard

別名:

1-(Carbazol-4-yloxy)-3-(isopropylamino)-2-propanol, 4-(2-Hydroxy-3-isopropylamino-propoxy)carbazole

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この商品について

実験式（ヒル表記法）:

C₁₈H₂₂N₂O₂

CAS番号:

57775-29-8

分子量:

298.38

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329757996

EC Number:

260-945-1

Beilstein/REAXYS Number:

3620576

MDL number:

MFCD00864588

主要文書

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製品名

カラゾロール, analytical standard

InChI key

BQXQGZPYHWWCEB-UHFFFAOYSA-N

InChI

1S/C18H22N2O2/c1-12(2)19-10-13(21)11-22-17-9-5-8-16-18(17)14-6-3-4-7-15(14)20-16/h3-9,12-13,19-21H,10-11H2,1-2H3

SMILES string

CC(C)NCC(O)COc1cccc2[nH]c3ccccc3c12

grade

analytical standard

assay

≥98.5% (HPLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable
solid phase extraction (SPE): suitable

mp

133-137 °C

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

Quality Level

200

General description

Spelco MIP SPEカートリッジ用スタンダード。詳しい情報を知りたい場合は、Supelcoの参考文献T407075, T706030, T706025をご請求ください。

Packaging

底の開いたガラス瓶内容物は内部に挿入され接着された円錐部に入っています。

Application

Carazolol may be used as a reference standard for the determination of the analyte:

In swine kidney by high-performance liquid chromatography with ultraviolet and fluorescence detection.
In animal tissues by high-performance liquid chromatography with electrochemical detection.

Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

GHS07

signalword

Warning

hcodes

H302,H315,H319,H335

pcodes

P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

保管分類

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

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Determination of tranquilisers and carazolol residues in animal tissue using high-performance liquid chromatography with electrochemical detection.

Rose MD and Shearer G

Journal of Chromatography A, 624(1-2), 471- 477 (1992)

Identifying conformational changes of the beta(2) adrenoceptor that enable accurate prediction of ligand/receptor interactions and screening for GPCR modulators.

Kimberly A Reynolds et al.

Journal of computer-aided molecular design, 23(5), 273-288 (2009-01-17)

The new beta(2) Adrenoceptor (beta(2)AR) crystal structures provide a high-resolution snapshot of receptor interactions with two particular partial inverse agonists, (-)-carazolol and timolol. However, both experimental and computational studies of GPCR structure are significantly complicated by the existence of multiple

Facile radiosynthesis of fluorine-18 labeled beta-blockers. Synthesis, radiolabeling, and ex vivo biodistribution of [18F]-(2S and 2R)-1-(1-fluoropropan-2-ylamino)-3-(m-tolyloxy)propan-2-ol.

Karin A Stephenson et al.

Journal of medicinal chemistry, 51(16), 5093-5100 (2008-07-29)

An efficient and general method has been developed for fluorine-18 labeling of beta-blockers that possess the propanolamine moiety. A new synthetically versatile intermediate, 3-(1-(benzyloxy)propan-2-yl)-2-oxooxazolidin-5-yl)methyl 4-methylbenzenesulfonate (13), was prepared and can be conjugated to any phenoxy core. To demonstrate the synthetic

Selective structure-based virtual screening for full and partial agonists of the beta2 adrenergic receptor.

Chris de Graaf et al.

Journal of medicinal chemistry, 51(16), 4978-4985 (2008-08-06)

The recently solved high-resolution X-ray structure of the beta2 adrenergic receptor has been challenged for its ability to discriminate inverse agonists/antagonists from partial/full agonists. Whereas the X-ray structure of the ground state receptor was unsuitable to distinguish true ligands with

Determination of residues of carazolol and a number of tranquilizers in swine kidney by high-performance liquid chromatography with ultraviolet and fluorescence detection.

Keukens HJ and Aerts MML

Journal of Chromatography A, 464, 149-161 (1991)

カラゾロール

analytical standard

サイズを選択してください

この商品について

主要文書

特性

製品名

InChI key

InChI

SMILES string

grade

assay

technique(s)

mp

application(s)

format

storage temp.

Quality Level

関連するカテゴリー

詳細

General description

Packaging

Application

安全性情報

pictograms

signalword

hcodes

pcodes

Hazard Classifications

target_organs

保管分類

wgk

flash_point_f

flash_point_c

ppe

資料

試験成績書（COA）

以前この製品を購入いただいたことがある場合

参考文献

テクニカルサービス