53787
カラゾロール
analytical standard
別名:
1-(Carbazol-4-yloxy)-3-(isopropylamino)-2-propanol, 4-(2-Hydroxy-3-isopropylamino-propoxy)carbazole
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この商品について
実験式（ヒル表記法）:
C18H22N2O2
CAS番号:
分子量:
298.38
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
260-945-1
Beilstein/REAXYS Number:
3620576
MDL number:
grade
analytical standard
Quality Level
assay
≥98.5% (HPLC)
technique(s)
HPLC: suitable, gas chromatography (GC): suitable, solid phase extraction (SPE): suitable
mp
133-137 °C
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
storage temp.
2-8°C
SMILES string
CC(C)NCC(O)COc1cccc2[nH]c3ccccc3c12
InChI
1S/C18H22N2O2/c1-12(2)19-10-13(21)11-22-17-9-5-8-16-18(17)14-6-3-4-7-15(14)20-16/h3-9,12-13,19-21H,10-11H2,1-2H3
InChI key
BQXQGZPYHWWCEB-UHFFFAOYSA-N
General description
Spelco MIP SPEカートリッジ用スタンダード。詳しい情報を知りたい場合は、Supelcoの参考文献T407075, T706030, T706025をご請求ください。
Application
Carazolol may be used as a reference standard for the determination of the analyte:
- In swine kidney by high-performance liquid chromatography with ultraviolet and fluorescence detection.
- In animal tissues by high-performance liquid chromatography with electrochemical detection.
Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Packaging
底の開いたガラス瓶内容物は内部に挿入され接着された円錐部に入っています。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
保管分類
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Determination of tranquilisers and carazolol residues in animal tissue using high-performance liquid chromatography with electrochemical detection.
Rose MD and Shearer G
Journal of Chromatography A, 624(1-2), 471- 477 (1992)
Kimberly A Reynolds et al.
Journal of computer-aided molecular design, 23(5), 273-288 (2009-01-17)
The new beta(2) Adrenoceptor (beta(2)AR) crystal structures provide a high-resolution snapshot of receptor interactions with two particular partial inverse agonists, (-)-carazolol and timolol. However, both experimental and computational studies of GPCR structure are significantly complicated by the existence of multiple
Karin A Stephenson et al.
Journal of medicinal chemistry, 51(16), 5093-5100 (2008-07-29)
An efficient and general method has been developed for fluorine-18 labeling of beta-blockers that possess the propanolamine moiety. A new synthetically versatile intermediate, 3-(1-(benzyloxy)propan-2-yl)-2-oxooxazolidin-5-yl)methyl 4-methylbenzenesulfonate (13), was prepared and can be conjugated to any phenoxy core. To demonstrate the synthetic