P6585
TWEEN® 20
Low-peroxide; Low-carbonyls
別名:
ポリエチレングリコールソルビタンモノラウラート, ポリオキシエチレンソルビタンモノラウラート
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この商品について
Quality Segment
description
non-ionic
form
viscous liquid
mol wt
~1228
contains
BHT as antioxidant
impurities
≤0.5 μmol/g Peroxides, ≤1.0 μmol/g Carbonyls, ≤3.0% water
refractive index
n20/D 1.468 (lit.)
CMC
0.06 mM (20-25°C)
transition temp
cloud point 76 °C
density
1.095 g/mL at 25 °C (lit.), 1.1 g/cm3 at 25 °C (lit.)
HLB
16.7
storage temp.
2-8°C
SMILES string
CCCCCCCCCCCC(=O)OCCOCC(C1C(C(CO1)OCCO)OCCO)OCCO
InChI
1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3
InChI key
HMFKFHLTUCJZJO-UHFFFAOYSA-N
General description
Tween®20 is a polyoxyethylene sorbitol ester that belongs to the polysorbate family. It is a nonionic detergent having a molecular weight of 1,225 daltons, assuming 20 ethylene oxide units, 1 sorbitol, and 1 lauric acid as the primary fatty acid. The ethylene oxide subunits are responsible for the hydrophilic nature of the surfactant, while the hydrocarbon chains provide the hydrophobic environment. Sorbitol forms the backbone ring to which the ethylene oxide polymers are attached.
Application
Tween 20 has been used along with PBS to wash plates in ELISA technique.
非イオン界面活性剤です。
Preparation Note
Purified to remove peroxides and aldehydes
Legal Information
TWEEN is a registered trademark of Croda International PLC
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保管分類
10 - Combustible liquids
wgk
WGK 3
flash_point_f
527.0 °F - Pensky-Martens closed cup
flash_point_c
275 °C - Pensky-Martens closed cup
ppe
Eyeshields, Gloves
Poke but don't pinch: risk assessment and venom metering in the western black widow spider, Latrodectus hesperus.
Nelsen DR
Animal behaviour, 89, 107-114 (2014)
Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: structure and degradation pathways.
Kerwin BA
Journal of Pharmaceutical Sciences, 97(8), 2924-2935 (2008)
John Ong et al.
Scientific reports, 10(1), 12429-12429 (2020-07-28)
Albumin-based hydrogels are increasingly attractive in tissue engineering because they provide a xeno-free, biocompatible and potentially patient-specific platform for tissue engineering and drug delivery. The majority of research on albumin hydrogels has focused on bovine serum albumin (BSA), leaving human