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Merck

PHR2582

塩酸ゲムシタビン

Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 50 mg

別名:

2′-デオキシ-2′,2′-ジフルオロシチジン;dFdC, LY-188011, dFdC, dFdCyd, ジェムザール(Lilly)

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この商品について

実験式(ヒル表記法):
C9H11F2N3O4 · HCl
CAS番号:
分子量:
299.66
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
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Quality Segment

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. Y0000675, traceable to USP 1288463

API family

gemcitabine

form

powder

CofA

current certificate can be downloaded

packaging

pkg of 50 mg

application(s)

pharmaceutical small molecule

storage temp.

2-8°C

SMILES string

Cl.NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)C2(F)F

InChI

1S/C9H11F2N3O4.ClH/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17;/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17);1H/t4-,6-,7-;/m1./s1

InChI key

OKKDEIYWILRZIA-OSZBKLCCSA-N

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Gemcitabine Hydrochloride can be used as an internal standard in estimation of gemcitabine hydrochloride in tablet dosage, injectable dosage form, parental dosage, and pharmaceutical dosage using HPLC methods.

Biochem/physiol Actions

ゲムシタビンは、臨床と研究の両方で広く使用されている抗腫瘍薬です。抗悪性腫瘍薬、代謝拮抗薬です。
ゲムシタビンは広く使用されている抗腫瘍薬かつ代謝拮抗薬です。

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC6253 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.


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pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Repr. 1B

保管分類

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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