モノクロナール抗ミオシン (骨格筋, 速筋型)−アルカリフォスファターゼ マウス宿主抗体

エピトープをミオシン重鎖に局在させます。骨格筋で見られるファスト（II型）イソミオシンおよび新生児イソミオシン分子を染色しますが、心筋、平滑筋または培養細胞中の非筋肉ミオシンは染色しません。ヒト横紋筋肉腫と反応しません。

Monoclonal Anti-Myosin (Skeletal, Fast) (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.

ウサギ筋肉のミオシン。

過去に負傷したスポーツマンから採取した血清サンプル中のミオシン（ファスト）濃度が、モノクローナルマウス抗ミオシン（骨格筋/ファスト）を一次抗体として1:90000に希釈して使用したウェスタンブロットで測定されました。

Monoclonal Anti-Myosin (Skeletal, Fast) Alkaline Phosphatase antibody produced in mouse has been used for the detection and localization of skeletal muscle fast and neonatal myosins using immunohistochemistry. It may be used in muscle fiber typing, in studies of in vivo and in vitro muscle development and in the diagnosis of rhabdomyosarcomas.

Monoclonal Anti-Myosin (Skeletal, Fast) specifically binds to an epitope in adult rat skeletal myosin heavy chains IIa, IIb and IId (IIx) (in fast-twitch fibers)†. The antibody product is also reactive in humans, bovines, cats, rabbits, mice, guinea pigs and chickens.

Myosin (Skeletal, Fast) is useful not only in fiber typing but also in detection of myogenic tumors. It enables retrospective as well as prospective fiber typing using formalin-fixed, paraffin-embedded material.

Myosins are motor proteins that interact with actin filaments to regulate cell movement. Myosins also modulate cell shape and signaling. Skeletal muscle myosins have three ′fast′ myosin heavy chains isoforms (IIa, IIx, and IIb), a ′slow′ beta-myosin heavy chain isoform and three major myosin light-chain (MLC) isoforms. These myosin isoforms regulate skeletal muscle shortening.

0.05M Trisバッファ-溶液 (pH 8.0, 1%BSA, 1mM MgCl₂, 50%グリセロ-ル, 15mMアジ化ナトリウム含有)。

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.