P8833
ピューロマイシン 二塩酸塩 Streptomyces alboniger由来
powder, non-animal origin, suitable for cell culture, BioReagent
別名:
3′-[α-アミノ-p-メトキシヒドロシンナムアミド]-3′-デオキシ-N,N-ジメチルアデノシン 二塩酸塩
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この商品について
製品名
ピューロマイシン 二塩酸塩 Streptomyces alboniger由来, powder, BioReagent, suitable for cell culture
biological source
Streptomyces alboniger
Quality Level
product line
BioReagent
assay
≥98% (HPLC)
form
powder
packaging
pkg of 10 mg, pkg of 100 mg, pkg of 25 mg
greener alternative product score
old score: 88
new score: 79
Find out more about DOZN™ Scoring
greener alternative product characteristics
Atom Economy
Design for Energy Efficiency
Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
technique(s)
cell culture | mammalian: suitable
color
yellow-white
UniProt accession no.
antibiotic activity spectrum
Gram-positive bacteria, neoplastics, parasites
application(s)
agriculture
greener alternative category
mode of action
protein synthesis | interferes
storage temp.
−20°C
SMILES string
Cl.Cl.COc1ccc(C[C@H](N)C(=O)N[C@H]2[C@@H](O)[C@@H](O[C@@H]2CO)n3cnc4c(ncnc34)N(C)C)cc1
InChI
1S/C22H29N7O5.2ClH/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12;;/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32);2*1H/t14-,15+,16+,18+,22+;;/m0../s1
InChI key
MKSVFGKWZLUTTO-FZFAUISWSA-N
General description
Application
- ピューロマイシン感受性アッセイ用の、ピューロマイシンストック溶液の調製。
- ピューロマイシン耐性セレクションマーカーを含むレンチウイルス感染細胞の選択。
Biochem/physiol Actions
耐性機序：ピューロマイシンアセチルトランスフェラーゼは、効果的な耐性遺伝子です。
抗菌スペクトル：本製品は、グラム陽性菌に対して活性があり、抗酸菌に対しては弱く、グラム陰性菌に対してさらに弱く活性を示します。 ピューロマイシンは、細菌、原虫、藻類、および哺乳類細胞の増殖を阻害し、素早く作用して、細胞の 99％を 2 日以内で死滅させます。
Preparation Note
Other Notes
Disclaimer
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signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
プロトコル
Stem cell reprogramming protocols to generate human induced pluripotent stem cells (iPSCs) including viral and non-viral RNA based methods.
資料
Antibiotics targeting bacterial ribosomes disrupt protein synthesis, a key process in bacterial growth inhibition.
Antibiotic kill curve is a dose response experiment in which mammalian cells are subjected to increasing amounts of selection antibiotic
Overview on how to maintain proper cell culture laboratory safety including steps on performing lab risk assessments, surface disinfection, biohazard and waste removal. Free ECACC handbook download.
関連コンテンツ
Learn how to use our cell culture tested, ready-to-use MilliShot™ single dose antibiotic solutions, conveniently packaged in one-time use vials.