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Merck

1705006

USP

L-チロシン

United States Pharmacopeia (USP) Reference Standard

別名:

(S)-2-アミノ-3-(4-ヒドロキシフェニル)プロピオン酸, 3-(4-ヒドロキシフェニル)-L-アラニン

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この商品について

化学式:
4-(HO)C6H4CH2CH(NH2)CO2H
CAS番号:
60-18-4
分子量:
181.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329751451
MDL number:
MFCD00002606
Beilstein/REAXYS Number:
392441

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InChI

1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1

SMILES string

N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI key

OUYCCCASQSFEME-QMMMGPOBSA-N

grade

pharmaceutical primary standard

API family

tyrosine

form

fine crystals

manufacturer/tradename

USP

mp

>300 °C (dec.) (lit.)

application(s)

USP Biologics
pharmaceutical (small molecule)

format

neat

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関連するカテゴリー

Other Notes

ドーパミンやその他のカテコールアミンのアミノ酸前駆物質です。
Sales restrictions may apply.
This product is part of USP Biologics Program.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

ʟ-Tyrosine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Tyrosine
  • Glycyl-l-tyrosine
  • Levodopa
  • N-Acetyltyrosine
  • Hyaluronidase Injection

General description

ʟ-Tyrosine is a non-essential amino acid involved in the biosynthesis of catecholamines, thyroid hormones, and melanin. The USP ʟ-Tyrosine standard guarantees the purity and quality of this amino acid, supporting its use in peptide synthesis, cell culture media, and therapeutic development.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

flash_point_f

Not applicable

flash_point_c

Not applicable

保管分類

11 - Combustible Solids

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

1705006-500MG:

jan

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試験成績書（COA）

Lot/Batch Number

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Andrzej Slominski et al.
Pigment cell & melanoma research, 25(1), 14-27 (2011-08-13)
There is evidence that L-tyrosine and L-dihydroxyphenylalanine (L-DOPA), besides serving as substrates and intermediates of melanogenesis, are also bioregulatory agents acting not only as inducers and positive regulators of melanogenesis but also as regulators of other cellular functions. These can
Maria B Feeney et al.
Antioxidants & redox signaling, 17(11), 1571-1579 (2012-03-20)
The understanding of physiological and pathological processes involving protein oxidation, particularly under conditions of aging and oxidative stress, can be aided by proteomic identification of proteins that accumulate oxidative post-translational modifications only if these detected modifications are connected to functional
Verena Rahm et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(4), 546-550 (2014-02-26)
Low-grade gliomas (LGGs) may harbor malignant foci, which are characterized by increased tumor cellularity and angiogenesis. We used diffusion-weighted MR imaging (apparent diffusion coefficient [ADC]) and PET with the amino acid O-(2-(18)F-fluorethyl)-L-tyrosine ((18)F-FET) to search for focal changes of diffusion
Daniel T Patton et al.
Journal of immunology (Baltimore, Md. : 1950), 193(7), 3446-3455 (2014-08-22)
IL-7 is critical for murine T and B cell development and survival and plays a significant role in lymphoblastic leukemia in both humans and mice. We evaluated the role of the IL-7Rα Tyr(449) cytoplasmic SH2-binding motif in IL-7-mediated B cell
Sharon L Bourke et al.
Advanced drug delivery reviews, 55(4), 447-466 (2003-04-23)
The natural amino acid L-tyrosine is a major nutrient having a phenolic hydroxyl group. This feature makes it possible to use derivatives of tyrosine dipeptide as a motif to generate diphenolic monomers, which are important building blocks for the design
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