F9128
5′-(4-Fluorosulfonylbenzoyl)adenosine hydrochloride
≥95% (TLC), synthetic (organic), powder
동의어(들):
Adenosine-5′-(4-fluorosulfonylbenzoate) hydrochloride, FSBA
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C17H16FN5O7S · HCl
CAS 번호:
Molecular Weight:
489.86
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Beilstein/REAXYS Number:
8178939
Assay:
≥95% (TLC)
Biological source:
synthetic (organic)
Form:
powder
Solubility:
methanol: 50 mg/mL, clear, colorless
Storage temp.:
−20°C
제품 이름
5′-(4-Fluorosulfonylbenzoyl)adenosine hydrochloride,
biological source
synthetic (organic)
Quality Segment
assay
≥95% (TLC)
form
powder
solubility
methanol: 50 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
Cl[H].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COC(=O)c4ccc(cc4)S(F)(=O)=O)[C@@H](O)[C@H]3O
InChI
1S/C17H16FN5O7S.ClH/c18-31(27,28)9-3-1-8(2-4-9)17(26)29-5-10-12(24)13(25)16(30-10)23-7-22-11-14(19)20-6-21-15(11)23;/h1-4,6-7,10,12-13,16,24-25H,5H2,(H2,19,20,21);1H/t10-,12-,13-,16-;/m1./s1
InChI key
ZUHVYHQVJYIHPN-KHXPSBENSA-N
Application
5′-(4-Fluorosulfonylbenzoyl)adenosine hydrochloride has been used to incubate with Ime2 (inducer of meiosis 2) to determine the sensitivity of Ime2 to the adenosine triphosphate (ATP) analog 5′-fluorosulfonylbenzoyladenosine (FSBA).
5′-(4-Fluorosulfonylbenzoyl)adenosine (FSBA) is an ATP analog used to study the mechanism of action of wortmannin. FSBA has been used to study vesicular transport in intestinal cells such as Caco-2, and to covalently modify residues in the nucleotide-binding domains (NBDs) of various ATPases, kinases, and other proteins.
Biochem/physiol Actions
5′-(4-Fluorosulfonylbenzoyl)adenosine helps to recognize adenosine triphosphate (ATP)-binding sites in kinases due to its reaction with nucleophilic amino acids happening within these motifs.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
저장 등급
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)