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Merck

SCP0096

Caspase Substrate

≥95% (HPLC), lyophilized

Synonym(s):

Ac-LETD-AFC, Ac-Leu-Glu-Thr-Asp-7-amino-4-trifluoromethyl coumarin

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About This Item

Empirical Formula (Hill Notation):
C31H38N5O12
Molecular Weight:
672.66
UNSPSC Code:
12352202
NACRES:
NA.32
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Product Name

Caspase Substrate,

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥80%

storage condition

protect from light

storage temp.

−20°C

Gene Information

human ... CASP8(841)

Biochem/physiol Actions

The peptide Ac-Leu-Glu-Thr-Asp-AFC, or Ac-LETD-AFC, is a fluorogenic substrate for caspase-8. The tetrapeptide sequence LETD is recognized as an ideal cleavage sequence for caspase-8.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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