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Merck

06-891

Anti-SMRTe Antibody

Upstate®, from rabbit

동의어(들):

Anti-CTG26, Anti-N-CoR2, Anti-SMAP270, Anti-SMRT, Anti-SMRTE, Anti-SMRTE-tau, Anti-TNRC14, Anti-TRAC, Anti-TRAC-1, Anti-TRAC1

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크기 선택


제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ChIP, ICC, WB
Citations:
35
기술 서비스
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도움 문의

biological source

rabbit

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

ChIP: suitable, immunocytochemistry: suitable, western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

General description

270kDa, 180kDa and 80kDa
SMRT is 1495 amino acids and contains an 8 amino acid sequence that is not present in SMRTe (SMRT-extended), which contains 2514 amino acids. SMRTe contains an N-terminal sequence spanning over 1,000 amino acids that is not present in SMRT, but that shows significant similarity with N-CoR. SMRTe expression is regulated during cell cycle progression, suggesting a role for SMRTe in the regulation of cycle-specific gene expression in diverse signaling pathways.

Immunogen

GST fusion-protein corresponding to residues 1146-1349 of human SMRTe

Application

Anti-SMRTe Antibody is a high quality Rabbit Polyclonal Antibody for the detection of SMRTe & has been validated in ChIP, ICC & WB.
Research Category
Protein Trafficking

Epigenetics & Nuclear Function
Research Sub Category
RNA Metabolism & Binding Proteins

Histones

RNA Binding Protein (RBP)

Biochem/physiol Actions

SMRT isoforms

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A chromatography

Preparation Note

Store at 2–8°C

Analysis Note

Control
Mouse brain nuclear extract
routinely evaluated by immunoblot on nuclear fraction from murine brain

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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저장 등급

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response.
Venteclef, N; Jakobsson, T; Ehrlund, A; Damdimopoulos, A; Mikkonen, L; Ellis, E; Nilsson et al.
Genes & Development null
NCoR1 and SMRT play unique roles in thyroid hormone action in vivo.
Shimizu, H; Astapova, I; Ye, F; Bilban, M; Cohen, RN; Hollenberg, AN
Molecular and cellular biology null
SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers.
Chen, J D, et al.
Proceedings of the National Academy of Sciences of the USA, 93, 7567-7571 (1996)
The Flt3 internal tandem duplication mutant inhibits the function of transcriptional repressors by blocking interactions with SMRT.
Takahashi, S; McConnell, MJ; Harigae, H; Kaku, M; Sasaki, T; Melnick, AM; Licht, JD
Blood null
Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression.
Aguilera, C; Hoya-Arias, R; Haegeman, G; Espinosa, L; Bigas, A
Proceedings of the National Academy of Sciences of the USA null

국제 무역 품목 번호

SKUGTIN
06-89104053252333712

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